An intervention (APA program) will be offered to patients hospitalized in the conventional hospitalization department of the medical oncology department.

At entry, after presenting the study and obtaining non-opposition from patients, an initial assessment will be carried out before the APA program.

At the end of the initial assessment, an APA program supervised (individually and in a room) by an APA teacher will be offered to patients. The sessions will be offered daily to patients (maximum 5 times/week). They will last on average 20 minutes each depending on the fatigue, pain and fitness of the patients. The objectives pursued are mainly an improvement in functional independence and mobility.

Content of the APA program:

* Strengthening of the lower limbs: Exercises alternating different regimes of muscular contractions (eccentric, concentric and isometric), with the use of elastics, balls or even body weight. These exercises will mainly work the quadriceps and hamstrings.
* Upper limb strengthening: Exercises focused on eccentric and concentric contraction regimes, in a global movement approach (as opposed to a segmental approach), with the use of elastics, dumbbells, weighted balls, etc. These exercises will work the muscles of the biceps, triceps, pectorals, deltoids and lats.
* Walking: In the room and/or in the corridor, with technical assistance (cane/walker, etc.) or human work
* Balance and proprioception: Balance work in a bi- and uni-pedal situation, statically and dynamically (eyes open and closed) will be offered with the use of proprioception boards and/or mats combining if possible work in dual task.

adapted physical activity program (APA Program)

Quentin JACQUINOT, Dr

This is a non-randomized, non-controlled feasibility study which will take place at the Besançon University Hospital in the conventional hospitalization department.

It will be carried out with patients hospitalized in the conventional hospitalization department of the medical oncology department of Besançon University Hospital.

At entry, after presenting the study and obtaining non-opposition from patients, an initial assessment will be carried out before the APA program. This assessment will include an evaluation of physical parameters (measurements of body composition, functional capacities, autonomy in activities of daily living and muscular strength), as well as an evaluation of quality of life relating to health and motivation to practice physical activity.

At the end of the initial assessment, an APA program supervised (individually and in a room) by an APA teacher will be offered to patients. The sessions will be offered daily to patients (maximum 5 times/week). They will last on average 20 minutes each depending on the fatigue, pain and fitness of the patients. The objectives pursued are mainly an improvement in functional independence and mobility.

Study Evaluating the Feasibility of an Adapted Physical Activity Program During the Hospitalization Phase in Cancer Patients Undergoing Treatment

The main objective of the study is to validate that the proportion of patients having completed, from inclusion (D0), at least three supervised APA sessions of a minimum duration of 15 minutes, during the first 7 consecutive days of his hospitalization (P) is beyond a threshold considered uninteresting of 50% (P0)

To test the following hypotheses:

H0: a compliant patient rate \<= 50% is uninteresting (P\<=P0) H1: a compliant patient rate \> 80% is expected (P\>P1) With an A'Hern type design, a one-sided alpha risk of 2.5% and a power of 90%, it is required to include 28 evaluable patients in the study to test H0 vs H1.

Considering a rate of unevaluable patients of 10% it will be necessary to include 32 patients.

Hypothesis H0 will be rejected if 20 (71.4%) or more than 20 patients out of the first 28 evaluable are compliant.

* fat-free mass index and muscle mass,
* body protein content,
* metabolic activity index

- Score of Short Physical Performance Battery Test (Score of 0 =Faible performance to 12= Haute performance)

IADL Questionnaire IADL score 0 to 4

* IADL score = 0: dependent
* IADL score = 4 autonomous

QLQ-C30 questionnaire All of the scales and single-item measures range in score from 0 to 100. A high scale score represents a higher response level. Thus a high score for a functional scale represents a high / healthy level of functioning, a high score for the global health status / QoL represents a high QoL, but a high score for a symptom scale / item represents a high level of symptomatology / problems.

Questionnaire BREQ-2 The BREQ-2 is a 19 item questionnaire that measures the stages of the self-determination continuum with respect to motivation to exercise with a 5 point Likert scale (0=not true for me, 4=very true for me)

Perception of effort with te Borg scale CR10.

Scale of 0 (No exertion at all) to 10 (representing an extreme intensity of activity)

Visual analog scale (0 = no pain and 10 = very severe pain)

Visual analog scale (0 = no fatigue and 10 = very severe fatigue)

Number of sessions carried out out of the number planned

Likert scale (0= unsatisfiedt o 5 =very satisfied)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Study Evaluating the Feasibility of an Adapted Physical Activity Program During the Hospitalization Phase in Cancer Patients Undergoing Treatment	NCT06321744	Cancer	adapted physica...	18 Years -	Centre Hospitalier Universitaire de Besancon
Study Evaluating the Feasibility of an Adapted Physical Activity Program During the Hospitalization Phase in Cancer Patients Undergoing Treatment	NCT06321744	Cancer	adapted physica...	18 Years -	Centre Hospitalier Universitaire de Besancon

Spots Global Cancer Trial Database for adapted physical activity program (apa program)