Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Behaviors and Mental Disorders

Lung Neoplasms

Carcinoma, Non-Small-Cell Lung

Carcinoma

Aggression

Carcinoma, Bronchogenic

Bronchial Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

patients in this arm will receive aggressive thoracic radiotherapy.

The target of the radiotherapy includes primary tumor and the locoregional positive lymph nodes, with a dose(BED)≥53Gray(Gy)

Aggressive Thoracic Radiotherapy

Li chunming, master

Yu Gengsheng, master

Chunming LI, master

Gengsheng Yu, master

This phase II trial studies the safety and efficacy of aggressive thoracic radiotherapy in treating patients with non-small cell lung cancer that has not progressed after the first line systemic therapy. In this trial, patients with stage Ⅳ non small cell lung cancer who did not progress after first line systemic therapy will receive the aggressive thoracic radiotherapy, and the safety and efficacy of aggressive thoracic radiotherapy will be evaluated. The primary end points of the study are overall survival (OS), the secondary end points are local control rate, local progression free survival(LPFS), PFS, and toxicity and quality of life(QOL).

Aggressive Thoracic Radiotherapy for Stage Ⅳ Non Small Cell Lung Cancer

The Efficacy and Toxicity of Aggressive Thoracic Radiotherapy for Stage Ⅳ Non-Small Cell Lung Cancer Patients With Controlled Extrathoracic Disease

assess according to the National Cancer Institute-Common Terminology Criteria for Adverse Events 3.0

yu gengsheng

Vice director of Oncology department

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Aggressive Thoracic Radiotherapy for Stage Ⅳ Non Small Cell Lung Cancer	NCT03565120	Carcinoma, Non-... Stage IV Thoracic Radiot...	Aggressive Thor...	18 Years - 80 Years	Jiangmen Central Hospital
Aggressive Thoracic Radiotherapy for Stage Ⅳ Non Small Cell Lung Cancer	NCT03565120	Carcinoma, Non-... Stage IV Thoracic Radiot...	Aggressive Thor...	18 Years - 80 Years	Jiangmen Central Hospital

Spots Global Cancer Trial Database for aggressive thoracic radiotherapy