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Tyrosine Kinase Inhibitors

Tyrosine

12 weeks of progressive strength training

12 weeks of supervised progressive strength training

Progressive strength training

Carsten Grüllich, MD

Friederike Scharhag-Rosenberger, PhD

Joachim Wiskamann, PhD

Dirk Jäger, Professor

Karen Steindorf, Professor

The purpose of this pilot study is to determine the effects of a 12-week resistance training program on cancer related fatigue in cancer patients receiving tyrosine kinase inhibitor (TKI) therapy. It is hypothesized that incidence and severity of cancer related fatigue can be reduced by exercise training in this population which leads to an improved treatment completion rate.

Reduction of Cancer Related Fatigue in Patients During TKI Therapy

Pilot Study on the Effects of Strength Training on Cancer Related Fatigue in Cancer Patients During Tyrosine Kinase Inhibitor Therapy

Assessed via the Multidimensional Fatigue Inventory (MFI).

Assessed isokinetically and isometrically via an IsoMed2000 test system.

Maximal oxygen uptake (VO2max) assessed in a maximal incremental cycling test.

Assessed via "Allgemeine Depressionsskala" (ADS).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Reduction of Cancer Related Fatigue in Patients During TKI Therapy	NCT01645150	All Tumor Entit...	Progressive str...	18 Years - 80 Years	German Cancer Research Center
Reduction of Cancer Related Fatigue in Patients During TKI Therapy	NCT01645150	All Tumor Entit...	Progressive str...	18 Years - 80 Years	German Cancer Research Center
Reduction of Cancer Related Fatigue in Patients During TKI Therapy	NCT01645150	All Tumor Entit...	Progressive str...	18 Years - 80 Years	German Cancer Research Center

Spots Global Cancer Trial Database for all tumor entities treated with tki therapy