Neoplasms

Blood and Lymph Conditions

Immune System Diseases

All Conditions

Rare Diseases

Lymphoma

Hodgkin Disease

Neoplasms by Histologic Type

Lymphoproliferative Disorders

Lymphatic Diseases

Immunoproliferative Disorders

Lymphosarcoma

Hodgkin Lymphoma

Currently planned dose levels in Part 1 are 50mg, 100mg, 200mg, 300mg, 450mg, 600mg and 740mg once daily

AUR105

Divyesh Dr Mandavia

Suresh Mr Oduru

Lakshmi Priyadarshini, MBBS

Bellala Ravi Shankar, MBBS

Santhosh Dr Vandanasetti

Rakesh Dr Neve

Viraj Vijay Dr Borgaonkar

Ghanshyam Dr Biswas

Sourav Dr Mishra

Lalatendu Dr Moharana

Deepam Dr Pushpam

This is a multi-center, open-label, First in Human, Phase 1 study of AUR 105 in adult patients with advanced malignancies.

The study will have two parts: a Dose Escalation Part and Dose Expansion Part.

This is a Phase I, Open label First in Human Study in adult patients with relapsed advanced malignancies.

The study will have two parts. Dose escalation part and Dose expansion part

First in Human, Dose Escalation, Dose Expansion Study of AUR105

A Phase 1, Open Label, Dose Escalation, Dose Expansion, Multicenter, First in Human (FIH) Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR105 in Patients With Relapsed Advanced Malignancies (SURYA-1)

Efficacy assessments overall response rate

Efficacy assessments- duration of response

Change in Tumor Specific Markers - CA-125 in ovarian cancer

Change in Tumor Specific Markers - PSA in Castrate Resistant Prostate Cancer

Change in Tumor Specific Markers - CEA in colorectal cancer

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
First in Human, Dose Escalation, Dose Expansion Study of AUR105	NCT05605119	Solid Tumor, Ad... Non-hodgkin Lym... Hodgkin Lymphom...	AUR105	18 Years - 99 Years	Aurigene Discovery Technologies Limited
First in Human, Dose Escalation, Dose Expansion Study of AUR105	NCT05605119	Solid Tumor, Ad... Non-hodgkin Lym... Hodgkin Lymphom...	AUR105	18 Years - 99 Years	Aurigene Discovery Technologies Limited

Spots Global Cancer Trial Database for aur105

Every month we try and update this database with for aur105 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for aur105

Every month we try and update this database with for aur105 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for aur105 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.