All Drugs and Chemicals

Antibodies

Antibodies, Bispecific

Immunoglobulins

B1962 is a PD-L1/VEGF bispecific antibody fusion protein.

B1962

Kongli zhu, Master

Caicun Zhou, MD

This study is to characterize the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of B1962, a PD-L1/VEGF bispecific antibody fusion protein, as a single agent in adult subjects with advanced solid tumor malignancies. The study consists of two parts: a once-weekly (QW) dosing phase and a biweekly (Q2W) dosing phase, which will explore the possibility of Q2W dosing of B1962 based on the PK data obtained in the QW phase. The study will determine the maximum tolerated dose (MTD), or recommended Phase 2 dose (RP2D) for B1962 as a single agent.

A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors

A Multicenter, Open-label, Dose-escalating Phase I Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors

Toxicity associated with the treatment of the investigational drug B1962

Changes of Eastern Cooperative Oncology Group score from baseline

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors	NCT05650385	Neoplasms Malig...	B1962	18 Years - 75 Years	Tasly Biopharmaceuticals Co., Ltd.
A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors	NCT05650385	Neoplasms Malig...	B1962	18 Years - 75 Years	Tasly Biopharmaceuticals Co., Ltd.

Spots Global Cancer Trial Database for b1962

Every month we try and update this database with for b1962 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for b1962

Every month we try and update this database with for b1962 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for b1962 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.