Digestive System Diseases

All Conditions

Neoplasms

Liver Diseases

Liver Neoplasms

Hepatic Insufficiency

Liver Failure

Gastrointestinal Diseases

Gastrointestinal Neoplasms

Digestive System Neoplasms

Hematinics

All Drugs and Chemicals

Liver Extracts

In this group , patients will undergo biliary reconstruction using surgical loupe

In this group , patients will undergo biliary reconstruction using microscope

Biliary reconstruction will be performed using surgical loupe

Surgical Loupes

Biliary reconstruction will be performed using microscope

Microscope

Comparison of biliary complications in right lobe living donor liver transplantation patients undergoing biliary reconstructions using microscope versus surgical loupes .

Liver transplantation (LT) is the most effective treatment modality in patients with end-stage liver disease and it is also established as a viable treatment option in the field of oncology. Living donor liver transplantation (LDLT) using the right lobe (RL) is a major achievement despite its technical challenges, which has created a significant increase in graft supply. While a secure bile duct anastomosis is one of the basic principles of a successful liver transplant procedure, biliary reconstruction remains the Achilles' heel of LDLT because of the high incidence of posttransplant biliary complications associated with significant recipient morbidity and mortality. Some of these complications are related to technical difficulties due to multiple small biliary orifices, particularly in right lobe grafts. In our center, we have been using microsurgical reconstruction technique for duct-to-duct biliary anastomosis in such grafts. The routine use of this technique has been shown to significantly decrease biliary complications in single-center retrospective studies. However, prospective controlled studies comparing microsurgical and standard biliary reconstruction techniques are lacking. In this study, our objective is to compare posttransplant complications of the two techniques of biliary reconstruction in RL LDLT.

40 patients will be included in the study. They will be randomly allocated in the equal groups.İn group 1 biliary anastomosis will be performed using surgical loupes and İn group 2 biliary anastomosis will be performed using microscope. The patients will be followed for one year after the transplant to compare biliary complications.

The patients will be randomly allocated in the equal groups.İn group 1 biliary anastomosis will be performed using surgical loupes and İn group 2 biliary anastomosis will be performed using microscope.

Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation

Prospective Randomized Single-center Trial Comparing Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation

Incidence of biliary complications after living donor liver transplantation

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation	NCT04618692	Liver Failure Liver Diseases Liver Cancer Liver Neoplasms Liver Dysfuncti...	Surgical Loupes Microscope	18 Years - 75 Years	Istanbul Medipol University Hospital
Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation	NCT04618692	Liver Failure Liver Diseases Liver Cancer Liver Neoplasms Liver Dysfuncti...	Surgical Loupes Microscope	18 Years - 75 Years	Istanbul Medipol University Hospital

Spots Global Cancer Trial Database for biliary anastomosis