Wounds and Injuries

All Conditions

Symptoms and General Pathology

Constriction, Pathologic

Jaundice

Jaundice, Obstructive

Pathological Conditions, Anatomical

biliary biopsy through a percutaneous approach during a percutaneous biliary drainage

biliary biopsy

Audrey Fohlen

To evaluate during a 7 months period the efficacy, safety and accuracy of percutaneous transluminal forceps biopsy combined with transhepatic biliary drainage in patients with biliary stricture

Biological parameters of liver function, histopathology of specimens, comparison with others clinical and pathological data (imaging follow up, percutaneous biopsy, surgical biopsy, endoscopic biopsy) were recorded Comparison between pathological findings of surgery or endoscopy or percutaneous biopsy and specimens coming from biliary forceps biopsy follow up of the patient 12 months after biopsy Evaluation of complications, accuracy

Percutaneous Transluminal Forceps Biopsy

Percutaneous Transluminal Forceps Biopsy Combined With Transhepatic Biliary Drainage in the Management of Patients With Obstructive Jaundice: Efficacy, Safety and Accuracy

Efficacy of PTBD : bilirubinemia after PTFB at Day 7

Accuracy of PTFB : percentage of true positive and true negative results by pathologists

Number of patients with PTFB related adverse-events as assessed by Society of Interventional Radiology Standards of Practice Committee classification

University Hospital, Caen

Neoplasms

Digestive System Diseases

Biliary Tract Neoplasms

Gallbladder Diseases

Gastrointestinal Neoplasms

Digestive System Neoplasms

Biliary Tract Diseases

Gastrointestinal Diseases

Add a transparent cap to the end of the SpyGlass choledochoscopy

Add a self-made transparent cap (made by cutting a silicone drainage tube) to the end of the SpyGlass choledochoscope, and then perform routine choledochoscopy and biopsy operations

Transparent cap

Yan Liu, MD

Liang Wu, MD

The transparent cap-assisted endoscope has the function of fixing field of view and increasing visual space. It has been widely used in gastrointestinal examination and treatment. In this study, the investigators intend to apply transparent cap-assisted choledochoscopy to endoscopic biliary tract exploration and biopsy to investigate whether transparent cap-assisted choledochoscopy can improve operability, visual field clarity, and biopsy accuracy.

Recently, endoscopy has become more widely used in clinical practice. A straightforward method of improving mucosal visualization involves attachment of a transparent cap to the end of the endoscope. It has been widely used in gastrointestinal examination and treatment.This is a before-after study. In patients with suspected bile duct stricture, tandem ERCP combined with SpyGlass choledochoscopy procedures were carried out on the same day in random order, first without a transparent cap and then with a cap (without-to-with), or first with a cap and then without a cap (with-to-without). The differences in maneuverability, visual field clarity and biopsy accuracy of choledochoscopy with and without transparent cap were recorded to explore the application prospect of transparent cap assisted choledochoscopy.

This is a before-after study. Transparent cap SpyGlass and standard SpyGlass were performed on the same patient successively.

Transparent Cap-assisted SpyGlass for Biliary Stricture

Application of Transparent Cap-assisted Digital Cholangioscopy (SpyGlassTM) for Biliary Stricture

The clearness of visual field was evaluated by the operating physician and was rated as "clear" or "not clear."

Comparison of intubation rates between transparent cap SpyGlass and standard SpyGlass

Biopsy accuracy between clear cap SpyGlass and standard SpyGlass was evaluated by comparing the coincidence rate of biopsy histopathology and postoperative pathology

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Percutaneous Transluminal Forceps Biopsy	NCT06039670	Biliary Strictu... Biopsy Wound Oncology	biliary biopsy	18 Years -	University Hospital, Caen
Percutaneous Transluminal Forceps Biopsy	NCT06039670	Biliary Strictu... Biopsy Wound Oncology	biliary biopsy	18 Years -	University Hospital, Caen
Transparent Cap-assisted SpyGlass for Biliary Stricture	NCT05320497	Bile Duct Stric... Endoscopic Retr... Biliary Disease Biliary Tract N...	Transparent cap	18 Years -	Affiliated Hospital to Academy of Military Medical Sciences
Transparent Cap-assisted SpyGlass for Biliary Stricture	NCT05320497	Bile Duct Stric... Endoscopic Retr... Biliary Disease Biliary Tract N...	Transparent cap	18 Years -	Affiliated Hospital to Academy of Military Medical Sciences

Spots Global Cancer Trial Database for biliary biopsy