Neoplasms

Digestive System Diseases

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Symptoms and General Pathology

Rare Diseases

Stomach Neoplasms

Gastroesophageal Reflux

Gastroparesis

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Stomach Diseases

Stomach Cancer

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Imidacloprid

Uncut Roux-en-Y Reconstruction will be used after laparoscopy-assisted distal gastrectomy for early gastric cancer.

Billroth II Reconstruction will be used after laparoscopy-assisted distal gastrectomy for early gastric cancer.

All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group.

Uncut Roux-en-Y Reconstruction

Billroth II Reconstruction

Dong Yang, postgraduate

Dong Yang, master

Quan Wang, proffessor

Quan Wang, professor

The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric.

To search which is the better reconstructions by comparing and analyzing the advantages and disadvantages between Uncut Roux-en-Y and Billroth II reconstructions after laparoscopy-assisted distal gastrectomy for gastric cancer.

Method: It's a prospective study including all patients underwent laparoscopy-assisted distal gastrectomy (LADG) in the First Hospital of Jilin University, from February 2016 to February 2017. All surgical procedures will be performed by the single surgery team, which is leaded by professor Wang Quan. The reconstruction method will be selected randomly from Uncut Roux-en-Y and Billroth II anastomosis by drawing lots preoperatively without distinct indications. Clinical data, operation data and perioperative complications and related physiological indexes of differences.

The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric

The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction

all patients of this clinical trial will be investigated by Gastroesophageal reflux disease questionnaire(GerdQ),and all patients whose score is beyond 8 will be collected.

The time of reconstruction operation will be recorded in the operating note by nurses in minutes.

In the morning of 1-6 days after operation , monitor the number of gastric juice's potential of hydrogen ( pH) value through gastric tube and write down the data. So if the data is greater than 7,the complication of bile reflux happened

During the operation the amount of blood loss will be recorded in the operating note by nurses in milliliters.

During the upper gastrointestinal radiography，if there is residual food,the meglumine diatrizoate will be separate and then write down the number.

During the upper gastrointestinal radiography,if there is meglumine diatrizoate refluxing to esophagus,it will be observed and written down in number.

Jilin University

Assisted Investigator

Billroth II reconstruction, in which a loop of jejunum is mobilized and anastomosed to the gastric remnant

Billroth II reconstruction

This is an additional surgical connection (anastomosis) created between two parts of the small intestine, specifically between the afferent (incoming) and efferent (outgoing) limbs of the jejunum near the gastrojejunostomy (the new connection between the stomach and small intestine created during a Billroth II procedure).

Braun Anastomosis

Zhaolun Cai, MD, PhD

Bo Zhang, MD

The primary aim of this trial is to rigorously evaluate the comparative benefits and potential risks associated with Billroth II reconstruction with Braun anastomosis versus Billroth II reconstruction alone following distal gastrectomy with D2 lymphadenectomy in patients diagnosed with gastric cancer. This assessment focuses on delineating the therapeutic efficacy, safety profile, and overall clinical outcomes of these two surgical approaches in treating this condition.

Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer

Billroth II With Braun Anastomosis Versus Billroth II Anastomosis After Radical Distal Gastrectomy With D2 Lymphadenectomy for Gastric Cancer: a Randomized Controlled Trial

The preoperative and postoperative QoL of patients between the two groups.

Changes in body weight (kg) or BMI from baseline

e.g., anastomotic leakage, anastomotic bleeding assessed by laboratory test in combination with clinical features, radiological diagnostic methods, endoscopy, diagnostic laparoscopy.

e.g., food residue and bile reflux (assessed according to the RGB classification).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric	NCT02694081	Gastric Cancer	Uncut Roux-en-Y... Billroth II Rec...	- 85 Years	Jilin University
Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer	NCT06229197	Gastric Cancer Surgery Anastomosis Gastrostomy	Billroth II rec... Braun Anastomos...	18 Years - 80 Years	Sichuan University

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