Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Anesthetics

Lateral wall urinary bladder tumors are resected transurethrally without obturator nerve block or relaxation under general anesthesia. If resection not possible because of adductor muscle contraction, patients undergo relaxation.

Bipolar transurethral resection of the urinary bladder (PlasmaKinetic, Gyrus, Fresenius)

Lateral wall urinary bladder tumors are resected transurethrally without obturator nerve block or relaxation under general anesthesia. If resection is not possible because of adductor muscle contraction, patients are treated by bipolar resection. If this is still not possible, they undergo relaxation.

Monopolar transurethral resection of the urinary bladder (Storz GmbH &Co., Erbotom, Purisole)

Daniel S Engeler, MD

This is a single-center, prospective, randomized, controlled trial comparing two established transurethral electrical resection methods of urinary bladder tumors regarding their risk of stimulating the obturator nerve.

One of the major safety issues with transurethral resection is bladder perforation as a consequence of obturator nerve stimulation followed by muscle contraction of. This is mostly a risk of resection of lateral bladder wall tumors near the course of the obturator nerve. It has been advocated that bipolar may be superior to monopolar resection, based on its different electrical properties. This is an important safety aspect for the patient.

Main study question: In patients with lateral wall urinary bladder tumors, is bipolar superior to monopolar transurethral electroresection regarding risk of stimulation of the obturator nerve without preoperative nerve block?

Safety Study of Bipolar Versus Monopolar Transurethral Resection of Bladder Tumors

Transurethral Resection of Bladder Tumors Without Obturator Nerve Block or Relaxation: Extent of Adductor Muscle Contraction With Monopolar Versus Bipolar Resection Technique

Successful resection of the neoplasm without relevant stimulation of the obturator nerve and consecutive contraction of the ipsilateral adductor muscles

Degree of severity of the complications (perforation of the bladder, intraoperative bleeding, postoperative bleeding, others) according to the Clavien-classification

Daniel Stephan Engeler

Leitender Arzt, Klinik für Urologie

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Safety Study of Bipolar Versus Monopolar Transurethral Resection of Bladder Tumors	NCT01446822	Neoplasm of Lat...	Bipolar transur... Monopolar trans...	18 Years -	Cantonal Hospital of St. Gallen
Safety Study of Bipolar Versus Monopolar Transurethral Resection of Bladder Tumors	NCT01446822	Neoplasm of Lat...	Bipolar transur... Monopolar trans...	18 Years -	Cantonal Hospital of St. Gallen

Spots Global Cancer Trial Database for bipolar transurethral resection of the urinary bladder (plasmakinetic, gyrus, fresenius)