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Central Nervous System Depressants

All Drugs and Chemicals

Analgesics

Bupivacaine

Dexmedetomidine

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Anesthetics, Local

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Analgesics, Non-Narcotic

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Ultrasonography (USG) guided bilateral TAP block:20 ml %0,25 concentration bupivacain

Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine

Ultrasonography (USG) guided bilateralTAP block:20 ml %0,25 concentration bupivacain

Bupivacain

bupivacain+dexmedetomidine

Beyza Seker, MD

Hazal E Guran Aytug, MD

Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients.

Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.

Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. With the increasing use of ultrasound guidance during peripheral nerve blocks, trunk blocks such as the transversus abdominis plane (TAP) block are widely used for analgesia after abdominal surgery.

The advantages of TAP block include being less invasive than epidural analgesia, lower incidence of hypotension, and shorter hospital stay. Due to these advantages, TAP block has become a widely preferred method.

Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. The study will be conducted in a tertiary oncology hospital in Turkey and 84 colorectal cancer patients will be included.

The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block

Comparison of the Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block in Colorectal Cancer Surgery

Numeric Rating Scales of two groups in postoperative period. The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Resident Anaesthesiologist

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block	NCT06370949	Colorectal Canc... Colorectal Neop...	Bupivacain bupivacain+dexm...	18 Years - 65 Years	Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block	NCT06370949	Colorectal Canc... Colorectal Neop...	Bupivacain bupivacain+dexm...	18 Years - 65 Years	Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Spots Global Cancer Trial Database for bupivacain+dexmedetomidine