Neoplasms

All Conditions

Mouth and Tooth Diseases

Head and Neck Neoplasms

Xerostomia

Salivary Gland Diseases

Mouth Diseases

Stomatognathic Diseases

Daily intake of oral moisturizing jelly 5 times/day for two months

Daily use of non-edible oral lubricating gel 5 times/day for two months

Gel-based artificial saliva is an edible non-nutritious gel intended to relieve dry mouth

Oral moisturizing jelly

A non-edible oral lubricating gel for dry mouth patients

Artificial saliva

Aroonwan Lam-ubol, DDS, PhD

This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.

Oral moisturizing jelly is a novel edible, gel-based artificial saliva. It has been proven effective in reducing dry mouth sign and symptoms in elderly patients with xerostomia. This randomized control trial intends to determine if continuous use of oral moisturizing jelly may be effective in reduction of signs and symptoms of dry mouth, improvement of biochemical properties of saliva, subjective swallow ability, appetite, tolerance to spicy food, energy intake and reduce umami taste recognition threshold.

Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

A Randomized Controlled Trial for Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients With Xerostomia

Evaluation of subjective dry mouth score by questionaire

Evaluation of objective dry mouth score by oral examination

Evaluation of salivary pH using pH indicator paper

Evaluation of salivary buffering capacity using a commercial saliva check buffer kit

Evaluation of number of fungal colonies of Candida spp. in saliva by culture

Evaluation of energy intake per day using dietary record and analysis

Evaluation of subjective swallow ability using EAT-10 questionaire

Evaluation of appetite using questionnaire

Evaluation of tolerance to spicy food using questionnaire

Evaluation of umami taste recognition threshold using filter paper disc method

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients	NCT03035825	Cancer of Head ... Radiation-Induc... Dry Mouth	Oral moisturizi... Artificial sali...	20 Years -	Dental Innovation Foundation Under Royal Patronage
Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients	NCT03035825	Cancer of Head ... Radiation-Induc... Dry Mouth	Oral moisturizi... Artificial sali...	20 Years -	Dental Innovation Foundation Under Royal Patronage

Spots Global Cancer Trial Database for cancer of head neck