Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Platelet Aggregation Inhibitors

Anesthetics

Propofol

Sevoflurane

Hypnotics and Sedatives

Anesthetics, Intravenous

Anesthetics, General

Anesthetics, Inhalation

Propofol will be administered as the anesthetic maintenance agent.

Sevoflurane will be administered as the anesthetic maintenance agent.

The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. Propofol and desflurane are most widely used as an anesthetic agent. Propofol and desflurane are known to block the muscarinic receptor in different ways.

The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

Propofol and Sevoflurane for Catheter-Related Bladder Discomfort

Effect of Propofol and Sevoflurane on Postoperative Catheter-Related Bladder Discomfort

Catheter-related bladder discomfort will be measured at 1 hour postoperatively (0:none, 1:mild, 2:moderate, 3:severe). Patients with score \>0 will be counted.

Mean blood pressure and heart rate will be measured at 0, 1, 5, 10 minute postoperatively. Measurement at 10 minute means Mean blood pressure and heart rate at the admission of post-anesthetic care unit.

Nausea will be measured at 0, 1, 6 and 24 hour postoperatively.

Vomiting will be measured at 0, 1, 6 and 24 hour postoperatively.

Dry mouth will be measured at 0, 1, 6 and 24 hour postoperatively.

Flushing will be measured at 0, 1, 6 and 24 hour postoperatively.

Blurred vision will be measured at 0, 1, 6 and 24 hour postoperatively.

Dizziness will be measured at 0, 1, 6 and 24 hour postoperatively.

The amount of analgesics will be measured at 0, 1, 6 and 24 hour postoperatively.

Seoul National University Hospital

Propofol will be administered as the anesthetic maintenance agent.

Propofol: Propofol will be administered.

Sevoflurane will be administered as the anesthetic maintenance agent.

Sevoflurane: Sevoflurane will be administered.

Total

Age, Categorical

Sex: Female, Male

Korea, Republic of

Region of Enrollment

Assistant professor

Catheter-related Bladder Discomfort

Hemodynamic Parameters

Nausea

Vomiting

Dry Mouth

Flushing

Patients with blurred vision were counted.

Blurred Vision

Dizziness

Patients infused with tramadol were counted.

Analgesics

Overall Study

Anti-Arrhythmia Agents

Adjuvants, Anesthesia

Respiratory System Agents

Atropine

Glycopyrrolate

Neuromuscular Blocking Agents

Bronchodilator Agents

Anti-Asthmatic Agents

Mydriatics

Parasympatholytics

Muscarinic Antagonists

Cholinergic Antagonists

Cholinergic Agents

Neurotransmitter Agents

Glycopyrrolate will be administered as the adjuncts of neuromuscular blocker reversal agent.

Atropine will be administered as the adjuncts of neuromuscular blocker reversal agent.

Hyun-Chang Kim, MD

Hee-Pyoung Park, PhD

We want to evaluate the efficacy of the glycopyrrolate and atropine for the prevention of catheter-related bladder discomfort.

The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. The adjuncts to reversal agents such as glycopyrrolate and atropine are known to block the muscarinic receptor in different ways.

We want to evaluate the efficacy of the glycopyrrolate and atropine for the prevention of catheter-related bladder discomfort.

Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort

Effect of Glycopyrrolate and Atropine as Adjuncts to Reversal of Non-Depolarizing Neuromuscular Blocking Agents on Postoperative Catheter-Related Bladder Discomfort

Catheter-related bladder discomfort will be measured at 1 hour postoperatively (0:none, 1:mild, 2:moderate, 3:severe).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Propofol and Sevoflurane for Catheter-Related Bladder Discomfort	NCT02252445	Catheter Site D... Complications Anesthesia Urinary Bladder...	Propofol Sevoflurane	19 Years - 80 Years	Seoul National University Hospital
Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort	NCT02228473	Catheter Site D... Complications Anesthesia Urinary Bladder...	Glycopyrrolate Atropine	19 Years - 80 Years	Seoul National University Hospital

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