Neoplasms

All Conditions

Rare Diseases

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Germ Cells Tumors

SMS before appointment detailing the date of consultation and exams to be performed before

short message service

Elise ROBERT

Elise Robert

This study will evaluate the impact of Short Message Service (SMS) on compliance with surveillance of patients with germ-cell tumors. Patients will be randomized in a 2:1 ratio to get 2 groups : (1) patients will receive reminder SMS before appointment detailing the date of consultation and exams to be performed before; (2) standard of care without SMS.

Study Evaluating the Impact of Short Message Service on Compliance With Surveillance of Patients With Germ-cell Tumors

Phase II, Open-label, Randomized, Non-comparative Study Evaluating the Impact of Short Message Service (SMS) on Compliance With Surveillance of Patients With Germ-cell Tumors. (TEXTIS Study)

Optimal compliance is defined according to the following 2 parameters:

* The patient comes to all the appointments, on the expected day, AND
* With all the biological and imaging exams previously scheduled by the physician.

Intermediate compliance is defined according to the following 2 parameters:

* The patient comes to all the appointments, but in one of the consultations, he delays his scheduled appointment of more than 3 weeks but less than 6 weeks OR
* Missing a biological or imaging exam.

Non compliance is defined according to the following 3 parameters:

The patient misses a consultation, without warning, OR

* He delays of more than 6 weeks his appointment of consultation, OR
* At least 2 biological or imaging exams requested by the oncologist are missing from all consultations.

It is evaluated with the following question: do you find that having reminder sms for your appointments and exams is useful? evaluated on a scale of 0 to 10 (0: useless, 10: useful)

Biological recurrence rate is defined by the increase in tumor markers (alpha-fetoprotein, lactic dehydrogenase, human chorionic gonadotropin).

Radiological recurrence rate is defined according to Response evaluation criteria in solid tumors (RECIST) criteria 1.1.

Centre Hospitalier Universitaire de Besancon

Interactive telephone reminder by a trained layperson with a standard script to remind return to the center for taking fecal tubes for CRC screening

Telephone reminder

No other

This is a randomized controlled study to compare the effectiveness of interactive telephone reminders by a layperson on enhancing compliance with CRC screening by FOBT, when compared with usual care (i.e. no intervention).

Colorectal cancer (CRC) is one of the major global health challenges. CRC is currently the third most common cancer in men and the second common in women worldwide, accounting for approximately 10% of all cancers. It leads to 8% of all cancer mortality in the world and it is the fourth most common cause of cancer deaths. There were 4,563 new cases and 3,893 new deaths in Hong Kong in 2012, while 47.4% of the new cases were diagnosed at stage III or above. In the past decades the Asia Pacific countries like China, South Korea, Japan, and Singapore have witnessed a two to three-fold rise in incidence, gradually catching up the figures in Western countries. The direct medical cost for the care of colorectal neoplasia was estimated US$45,115 for stage IV CRC in the initial year of care, bringing a substantial, global public health burden to the healthcare systems.

Randomized controlled studies have shown that CRC screening using Faecal Occult Blood Testing (FOBT) is effective in reducing cancer mortality by 15-33%. FOBT as a quick office-based procedure has the advantages of being non-invasive, inexpensive, acceptable, feasible, patient-friendly and devoid of needs for bowel preparation. A 25% relative risk reduction in CRC mortality was found for those attending at least one round of FOBT screening, according to a systematic review conducted in 2007. Guidelines from the US Preventive Services Task Force, the European Nations, the Asia Pacific Consensus statements and other authorities recommended FOBT as one of the first-line screening modalities, especially in resource-limited regions. Since yearly testing is recommended to maintain programmatic effectiveness, longitudinal adherence is a critical component of FOBT-based screening programs. Our previous study conducted in Hong Kong showed that the rate of compliance with CRC screening was declining since the first year of enrolment.

Nevertheless, it remains unknown whether interventions based on reminder systems could effectively enhance longitudinal compliance with FOBT, especially among those who have already enrolled in a CRC screening programme. Current evidence does not adequately compare whether interactive reminder are superior to usual care (i.e. no reminders).

Lay Tel Compliance Study

The Effectiveness of Telephone Reminders by a Layperson on Compliance With Colorectal Cancer Screening: an Open-label, Randomized Controlled Trial

Rate of completion of FOBT in the year of receiving the interventions/control

Rate of return to the centre for taking FOBT tubes in the year of receiving the interventions/control

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study Evaluating the Impact of Short Message Service on Compliance With Surveillance of Patients With Germ-cell Tumors	NCT03868176	Follow-up Compliance, Pat... Text Messaging Germ Cell Tumor	short message s...	18 Years -	Centre Hospitalier Universitaire de Besancon
Lay Tel Compliance Study	NCT03197116	CRC Screening Compliance, Pat...	Telephone remin... No other	50 Years - 75 Years	Chinese University of Hong Kong
Lay Tel Compliance Study	NCT03197116	CRC Screening Compliance, Pat...	Telephone remin... No other	50 Years - 75 Years	Chinese University of Hong Kong

Spots Global Cancer Trial Database for compliance, patient