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Meals will include approximately 1 ½ cups of cooked legumes, such as pinto, baked and navy beans as part of your 2 daily main dishes (lunch and dinner) and additional foods and snacks, preferably from the recommended healthy foods list. The smartpill will be administered at the end of the study.

Meals will be healthy, typical American foods (without legumes) for 2 daily main dishes and additional foods and snacks, preferably from the recommended healthy foods list.The smartpill will be administered at the end of the study.

about 1 1/2 cups of legumes included in lunch and dinner meals

Legume diet group

Control diet group

to assess how long food takes to pass through the digestive system

Smartpill

legumes

Terry J Hartman, PhD, MPH, RD

This pilot study is designed to test the effects of a high legume (dried bean) diet on hunger and other indicators of health over the course of eight weeks, compared to a more conventional healthy diet.

The goal of the currently proposed study is to conduct a randomized controlled feeding pilot study within a more diverse population also at high risk for colorectal carcinoma (CRC) to evaluate whether a high-legume diet will result in increased satiety and in turn will facilitate reduced energy intake and weight loss compared to a control diet provided under similar conditions. In addition, explore potential beneficial effects of the high-legume diet on gastric emptying and circulating levels of appetite-regulating hormones and other biomarkers. Dietary behaviors that are even moderately more satiating over time have the potential to enhance weight loss and could lead to a significant public health impact among populations at high risk for colorectal carcinoma (CRC) and other chronic diseases.

Towards the end of the study, the participants will do an additional test, looking at how long food takes to pass through the digestive system using a SmartPill capsule. The SmartPill is a pill about the size of a large multivitamin that can measure pH, pressure, and temperature changes, which it uses to assess where in the digestive tract it is. The participant swallows the pill, and carries around a receiver that is about the size of a deck of cards for the next 3-5 days. The SmartPill is expelled, and the receiver notifies the participant that they can return the receiver to the study personnel.

Legume Diet Satiety Pilot Study

Legume Diet Satiety and Weight Loss Pilot Study

Evaluate the effects of a high-legume diet compared to a control diet with a similar macronutrient profile on weight change in a randomized controlled feeding study.

Compare the effects of the high-legume and control diets on gastric emptying time

Compare the effects of the high-legume and control diets on plasma insulin level in a meal response time (30 min) course experiment.

Compare the effects of the high-legume and control diets on self-reported dietary intake measured by telephone 24-hour dietary recalls.

Use self-reported satiety questionnaire to compare short-term responses to test meals.

Emory University

Terry Hartman PhD, MPH, RD

Meals will include approximately 1 ½ cups of cooked legumes, such as pinto, baked and navy beans as part of your 2 daily main dishes (lunch and dinner) and additional foods and snacks, preferably from the recommended healthy foods list. The smartpill will be administered at the end of the study.

Legume diet group: about 1 1/2 cups of legumes included in lunch and dinner meals

Smartpill: to assess how long food takes to pass through the digestive system

legumes: about 1 1/2 cups of legumes included in lunch and dinner meals

Legume Diet Group

Meals will be healthy, typical American foods (without legumes) for 2 daily main dishes and additional foods and snacks, preferably from the recommended healthy foods list.The smartpill will be administered at the end of the study.

Control diet group: no legumes in lunch or dinner meals

Smartpill: to assess how long food takes to pass through the digestive system

Spots Global Cancer Trial Database for control diet group