Neoplasms

Digestive System Diseases

All Conditions

Rare Diseases

Stomach Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Stomach Diseases

Stomach Cancer

Central Nervous System Depressants

All Drugs and Chemicals

Analgesics

Anesthetics

Analgesics, Opioid

Analgesics, Non-Narcotic

Normal meal allowed until 6 h before surgery and Carbohydrate drink until 2 h before surgery

ERAS protocols

No nasogastric placement; if used, remove on the 1st postoperative day

On the 1st postoperative day Nasogastric catheter removed /Urinary catheter removed.

Oral non-opioid analgesia/Drinking 0.5L liquid. Active mobilisation

On the 2nd postoperative day：Drains removed Oral diet was initiated

3-4th postoperative day： Stop oral non opioid analgesia

On the5-6th postoperative day Check discharge criteria

No solid foods at dinner before surgery and no liquids 12 h before surgery. Routine bowel preparation Nasogastric placement on the morning of surgery

conventional pathway group

Routine use of anesthesia medicine. Standard 5-trocar laparoscopy-assisted procedure. I.V. fluids not restricted (Ringer's lactate 20 ml/kg in the first hour, then at the rate of 10-12 ml/kg/h) Routine use of abdominal drainage tubes and placement of catheters.

1st postoperative day: Keep Nasogastric catheter Removal of urinary catheter Opioid analgesic by intramuscular injection Parenteral nutrition until flatus. I.V. fluids not restricted Mobilization in bed

2nd postoperative day Patient is advised to get out of bed until 24-48h after surgery

3-4th postoperative day： Remove nasogastric tube after flatus Oral liquids started. Encouraged to walk in the ward.

5-6th postoperative day：Oral diet was changed from liquids to semi-fluids and normal food.

Drains removed

Quan Wang, Doctor

The investigators designed a prospective randomized, controlled clinical trial then recruited 149 consecutive advanced gastric cancer patients. Further divided into a ERAS group (n=73) and a conventional pathway group (n=76). Surgical technique in both groups was same laparoscopic-assisted gastrectomy with D2 lymphadenectomy. Compared outcomes included clinical parameters and serum indicators.

Enhanced recovery after surgery combined with laparoscopic-assisted gastrectomy was successfully carried out in this study. Recovery parameters such as the length of time to return to normal diet,mean hospital stay (d) were recorded.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins	NCT02348229	Gastric Cancer	ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols conventional pa... conventional pa... conventional pa... conventional pa... conventional pa... conventional pa...	18 Years - 75 Years	The First Hospital of Jilin University
Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins	NCT02348229	Gastric Cancer	ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols conventional pa... conventional pa... conventional pa... conventional pa... conventional pa... conventional pa...	18 Years - 75 Years	The First Hospital of Jilin University
Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins	NCT02348229	Gastric Cancer	ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols ERAS protocols conventional pa... conventional pa... conventional pa... conventional pa... conventional pa... conventional pa...	18 Years - 75 Years	The First Hospital of Jilin University

Spots Global Cancer Trial Database for conventional pathway group