Core + Green Foods Monitoring + Nutrition Goals + Supportive Text Messages + All Lessons

Core + Green Foods Monitoring + Nutrition Goals + Supportive Text Messages + Weekly Lessons

Core + Green Foods Monitoring + Nutrition Goals + No Supportive Text Messages + All Lessons

Core + Green Foods Monitoring + Nutrition Goals + No Supportive Text Messages + Weekly Lessons

Core + Green Foods Monitoring + No Nutrition Goals + Supportive Text Messages + All Lessons

Core + Green Foods Monitoring + No Nutrition Goals + Supportive Text Messages + Weekly Lessons

Core + Green Foods Monitoring + No Nutrition Goals + No Supportive Text Messages + All Lessons

Core + Green Foods Monitoring + No Nutrition Goals + No Supportive Text Messages + Weekly Lessons

Core + Red Foods Monitoring + Nutrition Goals + Supportive Text Messages + All Lessons

Core + Red Foods Monitoring + Nutrition Goals + Supportive Text Messages + Weekly Lessons

Core + Red Foods Monitoring + Nutrition Goals + No Supportive Text Messages + All Lessons

Core + Red Foods Monitoring + Nutrition Goals + No Supportive Text Messages + Weekly Lessons

Core + Red Foods Monitoring + No Nutrition Goals + Supportive Text Messages + All Lessons

Core + Red Foods Monitoring + No Nutrition Goals + Supportive Text Messages + Weekly Lessons

Core + Red Foods Monitoring + No Nutrition Goals + No Supportive Text Messages + All Lessons

Core + Red Foods Monitoring + No Nutrition Goals + No Supportive Text Messages + Weekly Lessons

The core intervention will include behavioral lessons, activity tracker, weekly adaptive physical activity goals, weekly tailored feedback summary.

Core

Simplified diet monitoring using smartphone tracking of green foods using a traffic light approach.

Simplified Nutrition Monitoring (Green)

Simplified diet monitoring using smartphone tracking of red foods using a traffic light approach.

Behavioral: Simplified Nutrition Monitoring (Red)

Participant will be assigned a personalized weekly nutrition goal related to nutrition monitoring condition.

Nutrition Goals (Yes)

Participant will not be assigned a personalized weekly nutrition goal.

Nutrition Goals (No)

Participant will receive up to 5 supportive text-messages from the study staff per week.

Supportive Text Messages (Yes)

Participant will not receive supportive text-messages.

Supportive Text Messages (No)

All behavioral lessons will be made available to participant simultaneously.

Lesson Delivery (Once)

A new behavioral lesson will be made available to participant weekly throughout the 12 weeks.

Lesson Delivery (Weekly)

Erin Coffman

Carmina Valle

Will Pulley

Aspen R Yordy

Erin M Coffman, MA

The purpose of this pilot randomized factorial trial is to test the feasibility, acceptability, and effects of a theory-based mobile physical activity and nutrition intervention designed specifically for young adult cancer survivors to increase physical activity and diet quality.

There are around 1 million young adult cancer survivors in the United States. Young adult cancer survivors are an underserved and vulnerable subgroup of survivors that experience increased risk for chronic health conditions like cardiovascular disease, metabolic syndrome, secondary cancers, premature aging, and premature death. Modifiable lifestyle factors contribute to and compound risks for late and long-term health effects from cancer and its treatment, making them high-impact targets for behavioral interventions. International consensus guidelines recommend cancer survivors of all ages be physically active, consume a healthy diet, and achieve and maintain a healthy weight. Fewer than half of young adult cancer survivors meet guideline recommendations for vegetable intake, physical activity and the majority self-report having an overweight/obese BMI. To date, there are few physical activity interventions, and no nutritional interventions designed specifically for young adult cancer survivors. Digital behavior change interventions have emerged as feasible and efficacious approaches to reach and address unmet needs among young adult cancer survivors as they overcome barriers of time, flexibility, affordability, and access. Reaching these populations has been facilitated by digital tools like wearable devices that enable real-time data capture to guide the provision of individualized feedback and tailored goal setting based on personal progress. This pilot trial will use the Multiphase Optimization Strategy (MOST), an engineering-inspired framework, and a highly efficient experimental design to evaluate the feasibility of 4 intervention components to improve physical activity and nutrition behaviors among young adult cancer survivors. Young adult cancer survivors (n=80), diagnosed between ages 18-39, will be recruited to receive a core 3-month digital physical activity and nutrition intervention that includes evidence-based lessons and behavioral skills training with an emphasis on adherence to American Cancer Society (ACS) guidelines for cancer survivors and self-monitoring of physical activity and dietary behaviors. Additionally, participants will be randomized to four intervention components--each with two levels-- including: 1) simplified dietary tracking (daily tracking of green (low-calorie, high nutrients) vs. red (high-calorie, high-fat, low nutrients) foods), 2) dietary goals using simplified approach (daily goals vs. no goals), 3) supportive text messages (yes vs. no), 4) lesson delivery (all provided once vs. weekly). Assessments of outcomes will be conducted at baseline, 6 weeks, and 3 months to accomplish the following specific aims: 1) Evaluate the feasibility and acceptability the intervention at 3 months; 2) Evaluate intervention effects on change in physical activity and diet quality; 3) Evaluate intervention effects on secondary outcomes at 6 weeks and 3 months; and 4) Explore whether theoretical constructs (perceived competence, self-regulation, self-efficacy, and perceived relatedness) mediated the effects of the intervention on change in health behaviors at 3 months.

This study uses a full factorial experimental design testing the efficacy of four intervention components, each with two levels

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

A Pilot Randomized Factorial Trial to Promote Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

Number of participants who agreed to participate divided by the number of months of recruitment.

Percentage of eligible participants who agreed to participate.

Number of intervention participants who completed 3-month measures divided by the number who consented to participate.

Ratings of program acceptability and satisfaction with the intervention, as measured by acceptability and satisfaction questionnaire.

Number of days physical activity tracked, as measured by Fitbit.

Number of days of complete dietary tracking.

Change in levels of physical activity, as measured by Fitbit, from baseline to 3 months. Participants will wear a Fitbit on their wrist during a 7 day period.

Moderate-to-vigorous physical activity will be defined as the change in self-reported weekly minutes of moderate-to-vigorous physical activity as measured by the Paffenbarger Activity Questionnaire from baseline to 12 weeks. The minimum is 0, no maximum. Higher numbers represent higher minutes of weekly moderate-to-vigorous physical activity.

Dietary intake will be defined as the change in HEI score as measured by the NCI's Automated Self-Administered 24-hour (ASA 24-hour) dietary recalls from baseline to 3 months.The HEI consists of 13 component scores, including: total fruit, whole fruit, total protein foods, total vegetables, greens and beans, whole grains, dairy, seafood and plant proteins, fatty acids, sodium, refined grains, added sugars, and saturated fats. The summation of the 13 component scores ranges from 0 to 100, with higher scores indicating closer compliance with the Dietary Guidelines for Americans.

Absolute weight change from baseline to 3 months. Weight will be objectively measured on a scale in the participant's home.

The FRAIL Questionnaire includes five components that assess: 1) self-reported fatigue (PROMIS Fatigue Short form), 2) weight loss, 3) comorbidities (11 items from UNC Health Registry Comorbidity Assessment), 4) difficulty with ambulation (1 item from PROMIS Physical Function Short Form), and 5) ability to overcome resistance (1 item from PROMIS Physical Function)). The number of positive responses for these components is summed to create the FRAIL index (range 0-5) and characterized as 0-1: robust, 2: prefrail, and 3+: frail. Changes in individual components and overall frailty scores from baseline to 3 months will be assessed.

Changes in health-related quality of life from baseline to 3 months as measured using the Adolescent and Young Adult (AYA)PROMIS PRO Core Battery. These measures assess relevant HRQoL domains for AYA cancer survivors that are most likely to be impacted during and after cancer treatment. The AYA PRO Core battery includes the following PROMIS short forms: depression, anxiety, fatigue, physical function, pain interference, emotional support, cognitive function, pain intensity. Each question has five responses ranging in value from 1 to 5, which are summed to find the total raw score. Total raw scores are translated to a T-score, standardized with a population mean of 50 and a standard deviation of 10. A higher PROMIS T-score represents more of the concept being measured.

Changes in perceived competence from baseline to 3 months as measured using the Perceived Competence Scale includes 4 items that measure perceived competence for nutrition and 4 items for physical activity. Ratings are on a 7-point Likert scale with higher scores indicating greater perceived competence for the behavior.

Changes in self-efficacy from baseline to 3 months as measured using the Nutrition and Physical Activity Self-Efficacy Scale, a 10-item scale that assesses an individual's confidence in their ability to eat healthy foods and exercise in the presence of barriers. Ratings are on a 4-point Likert scale with higher scores indicating greater self-efficacy for exercise and nutrition.

Changes in self-regulation from baseline to 3 months as measured using the Treatment Self-Regulation Questionnaire (TSRQ) will be used to assess autonomous and controlled motivation for making changes in diet (15 items) and physical activity (15 items). Ratings are on a 7-point Likert scale indicating agreement with statements regarding motivation for behavior change.

Changes in perceived autonomy support as measured using the Virtual Care Climate Questionnaire (VCCQ) a 15-item measure of perceived support for autonomy provided by the study team in a virtual care setting. Ratings are on a 7-point Likert scale with higher scores indicating a higher level of perceived autonomy support.

National Cancer Institute (NCI)

UNC Lineberger Comprehensive Cancer Center

Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

core, support calls, app+, app notifications

core, support calls, buddy, app notifications

core, support calls, online gym, app notifications

core, app+, buddy, online gym, app notifications

core, support calls, buddy, online gym, app notifications

core, buddy, online gym, app notifications

core, app+, online gym, app notifications

core, support calls, app+, buddy, online gym

core, support calls, app+, buddy, app notifications

core, support calls, app+, online gym, app notifications

core, support calls, app+, buddy, online gym, app notifications

The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Participants will receive 6 bi-weekly phone calls from study staff.

Support Calls

Participants will receive "deluxe" version of smartphone app with additional features.

App+

Participants will receive access to online exercise videos.

Online gym

Participants will receive motivational app notifications

App notifications

Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Buddy

The overall objective of the proposed research is to pilot test the feasibility and acceptability of a set of more scalable technology-supported physical activity promotion intervention strategies in breast cancer survivors using tMultiphase Optimization Strategy Trial (MOST) methodology. MOST involves highly efficient randomized experimentation to assess the effects of individual intervention strategies, and thereby identify which strategies and what strategy levels make the important contributions to the overall program's effect on physical activity. This information then guides assembly of an optimized physical activity program, that achieves target outcomes with least resource consumption and participant burden. The resulting intervention will have great potential for scalability because it uses technology (smartphones) participants already own and requires no on-site visits.

Optimization of Remotely Delivered Physical Activity Intervention for Breast Cancer Survivors

Designing With Dissemination in Mind: Optimization of a mHealth Physical Activity Intervention for Breast Cancer Survivors

Data collected in this study will be made available to other researchers in compliance with the NIH Data Sharing Policy.

Adherence during the 12 week intervention will be monitored continuously using study app. This measures the average percentage of days each participant randomized wore the Fitbit during weeks 1 to 12.

Percentage of participants retained at the end of the 12 week intervention of those randomized \[(# of participants randomized who completed at least 1 outcome assessment measure at 12 weeks)/ # randomized\*100\].

Percentage of individuals randomized of those who were sent a study screening survey

Physical activity will be measured at baseline and at 12 weeks. The ActiGraph accelerometer will be used. At each time point, participants will wear the device for 7 consecutive days during all waking hours, except when bathing or swimming. Each valid minute of wear time will be classified according to intensity (counts/min) using commonly accepted cut-points: sedentary (\<100), light activity (100-2019) and moderate/vigorous physical activity (≥2020).

Physical activity will be measured at baseline and at 24 weeks. The ActiGraph accelerometer will be used. At each time point, participants will wear the device for 7 consecutive days during all waking hours, except when bathing or swimming. Each valid minute of wear time will be classified according to intensity (counts/min) using commonly accepted cut-points: sedentary (\<100), light activity (100-2019) and moderate/vigorous physical activity (≥2020).

Fatigue is measured at baseline and 12 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-Fatigue 8a health measure. T-scores range from 33.1 to 77.8 Higher scores indicate more fatigue. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population.

Fatigue will be measured at baseline and 24 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-Fatigue 8a health measure. T-scores range from 33.1 to 77.8 Higher scores indicate more fatigue. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population.

Physical function will be measured at baseline and 12 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-physical function 20a health measure. T-scores range from 32.7 to 62.7. Higher scores indicate better physical functioning. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population.

Physical function will be measured at baseline and 24 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-physical function 20a health measure. T-scores range from 32.7 to 62.7. Higher scores indicate better physical functioning. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population. The treatment effect is calculated as the mean difference in the change in physical function between baseline and 24-weeks for each component on versus off.

Depression will be measured at baseline and 12 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-Depression 8a health measure. T-scores range from 38.2 to 81.3. Higher scores indicate more depression. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population.

Depression will be measured at baseline and 24 weeks using the Patient Reported Outcomes Measurement Information System (PROMIS)-Depression 8a health measure. T-scores range from 38.2 to 81.3. Higher scores indicate more depression. T-score metric with a mean of 50 and standard deviation of 10 in the U.S. general population.

Adherence during the 24-week study period will be monitored continuously using study app. This measure the average percentage of days each randomized participant wore the Fitbit from weeks 1 to 24.

Percentage of participants retained at 24 weeks of those randomized

Interleukin-6 (IL-6) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminescent immunoassay protocol.

Interleukin-6 (IL-6) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminscent immunoassay protocol.

Interleukin-10 (IL-10) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminscent immunoassay protocol.

Interleukin-10 (IL-10) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminscent immunoassay protocol. Higher IL-10 may have protective effects.

tumor necrosis factor-alpha (TNFα) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminscent immunoassay protocol. Lower values are better.

tumor necrosis factor-alpha (TNFα) will be self-collected via finger prick to obtain dried blood spot and will be quantified using a standard multiplex electrochemiluminscent immunoassay protocol. TLower values are better.

C-reactive protein (CRP) will be self-collected via finger prick to obtain dried blood spot and will be quantified using ELISA. Lower values are better.

C-reactive protein (CRP) will be self-collected via finger prick to obtain dried blood spot and will be quantified using standard ELISA. Lower values are better.

Triglycerides are self-collected via finger prick to obtain a dried blood spot and quantified using a standard coupled enzymatic protocol.

Triglycerides are self-collected via finger prick to obtain a dried blood spot and quantified using a standard coupled enzymatic protocol. Lower values are better.

Blood glucose is self-collected via finger prick to obtain a dried blood spot and quantified using a standard coupled enzymatic protocol.

Blood Glucose is self-collected via finger prick to obtain a dried blood spot and quantified using a standard coupled enzymatic protocol.

High density lipoprotein cholesterol (HDL) is self-collected via finger prick to obtain a dried blood spot and quantified using a standard coupled enzymatic protocol.

Northwestern University

Assistant Professor

core, support calls

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Experimental Condition #1

core, support calls, app+

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Experimental Condition #2

core, support calls, buddy

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #3

core, support calls, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Online gym: Participants will receive access to online exercise videos.

Experimental Condition #4

core, support calls, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App notifications: Participants will receive motivational app notifications

Experimental Condition #5

core, app+

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Experimental Condition #6

core, app+, buddy

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #7

core, app+, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

Experimental Condition #8

core, app+, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

App notifications: Participants will receive motivational app notifications

Experimental Condition #9

core, buddy

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #10

core, buddy, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Online gym: Participants will receive access to online exercise videos.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #11

core, buddy, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #12

core, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Online gym: Participants will receive access to online exercise videos.

Experimental Condition #13

core, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Experimental Condition #14

core, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App notifications: Participants will receive motivational app notifications

Experimental Condition #15

core, support calls, app+, buddy

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #16

core, support calls, app+, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

Experimental Condition #17

core, support calls, app+, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

App notifications: Participants will receive motivational app notifications

Experimental Condition #18

core, support calls, buddy, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Online gym: Participants will receive access to online exercise videos.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #19

core, support calls, buddy, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #20

core, support calls, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Experimental Condition #21

core, app+, buddy, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #22

core, app+, buddy, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #23

core, support calls, buddy, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #24

core, buddy, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #25

core, app+, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Experimental Condition #26

core, support calls, app+, buddy, online gym

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #27

core, support calls, app+, buddy, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #28

core, support calls, app+, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Experimental Condition #29

core

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Experimental Condition #30

core, app+, buddy, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #31

core, support calls, app+, buddy, online gym, app notifications

Core: The core intervention will include educational materials, access to a basic smartphone app and a Fitbit.

Support Calls: Participants will receive 6 bi-weekly phone calls from study staff.

App+: Participants will receive "deluxe" version of smartphone app with additional features.

Online gym: Participants will receive access to online exercise videos.

App notifications: Participants will receive motivational app notifications

Buddy: Participants will choose a buddy to receive a Fitbit and support them during the intervention.

Experimental Condition #32

Total

Age, Continuous

Sex: Female, Male

Ethnicity (NIH/OMB)

Race (NIH/OMB)

Number of Participants Randomized

Siobhan Phillips

All participants randomized regardless of individual randomly assigned combination of On- or Off levels of all intervention factors.

All Reporting Groups

Adherence to a 12 Week Technology Supported Physical Activity Intervention

Participant Retention

Intervention Reach

"On" Group Change

"Off" Group Change

Participants receive 6 bi-weekly phone calls from study staff.

One participant was excluded because data values were deemed implausible. In a full factorial trial, participants are randomized to receive each intervention component (support calls, buddy, app notifications, online gym, app+) "on" or "off." Participants randomized to "on" are compared to those randomized to "off." All participants get the core intervention so there is no comparison group.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Physical Activity and Healthy Eating Among Young Adult Cancer Survivors	NCT05887401	Physical Activi... Neoplasms Cancer	Core Simplified Nutr... Behavioral: Sim... Nutrition Goals... Nutrition Goals... Supportive Text... Supportive Text... Lesson Delivery... Lesson Delivery...	18 Years - 39 Years	UNC Lineberger Comprehensive Cancer Center
Optimization of Remotely Delivered Physical Activity Intervention for Breast Cancer Survivors	NCT03131440	Breast Cancer F... Physical Activi...	Core Support Calls App+ Online gym App notificatio... Buddy	18 Years -	Northwestern University
Optimization of Remotely Delivered Physical Activity Intervention for Breast Cancer Survivors	NCT03131440	Breast Cancer F... Physical Activi...	Core Support Calls App+ Online gym App notificatio... Buddy	18 Years -	Northwestern University

Spots Global Cancer Trial Database for core

Every month we try and update this database with for core cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for core

Every month we try and update this database with for core cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for core cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.