Symptoms and General Pathology

All Conditions

Wounds and Injuries

Behaviors and Mental Disorders

Inflammation

Hyperthermia

Fever

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Stress Disorders, Traumatic

Heat Stress Disorders

Patients subjected to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) due to primary or secondary peritoneal malignancy

During CRS, all visible peritoneal tumors are removed. Consequently micrometastasis are removed with hyperthermic intraperitoneal chemotherapy

CRS and HIPEC

Kuno Lehmann, MD, PhD

Dilmurodjon Eshmuminov, MD

Kuno Lehmann, Md. PhD

The purpose of this study is to assess the dynamics of inflammatory parameters in presence or absence of infectious complications after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is the treatment of choice in patients with primary or secondary peritoneal surface malignancies. However the survival benefit is achieved at the cost of increased morbidity and mortality due to an extensive surgery and intraoperative chemo-therapy. Among complications infectious complications are the most common. The early diagnosis of a potential fatal infection is therefore crucial to ensure a good outcome in patients.

Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

University of Zurich

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy	NCT02741167	Peritoneal Canc...	CRS and HIPEC	18 Years -	University of Zurich
Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy	NCT02741167	Peritoneal Canc...	CRS and HIPEC	18 Years -	University of Zurich
Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy	NCT02741167	Peritoneal Canc...	CRS and HIPEC	18 Years -	University of Zurich

Spots Global Cancer Trial Database for crs and hipec