Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

No preoperative imaging is performed for this group

Patients randomized to this group will undergo a preoperative CTA scan.

Patients randomized to this group will undergo a preoperative MRA scan.

Joan Lipa, MD, MSc

The purpose of this study is to determine whether preoperative abdominal imaging using either CT angiogram (CTA), or MR angiogram (MRA) will impact perforator dissection time, cost, and patient outcomes in DIEP flap breast reconstruction.

This study will prospectively compare the clinical, economic and patient outcomes of preoperative imaging using either CTA or MRA with those of no preoperative imaging in patients undergoing deep inferior epigastric perforator (DIEP) flap breast reconstruction. Subjects will randomly undergo either a CTA scan or an MRA scan, or no scan (control) preoperatively. An operative plan based on perforator size and course will be devised by an interventional radiologist and a plastic surgeon. The DIEP flap procedure will be planned for controls.

Subjects will not be told if the operative plan is changed intraoperatively. Flap dissection time and changes in operative plan will be recorded intraoperatively and surgeon stress will be evaluated following surgery. Pain and narcotic use will be evaluated preoperatively and on days 1-4 postoperatively. The Breast-Q will be completed preoperatively and at 3 weeks, 3 months and 12 months postoperatively. Groups will be compared in terms of all variables measured.

Preoperative Imaging in DIEP Flap Breast Reconstruction

Preoperative Imagining in DIEP Flap Breast Reconstruction: A Randomized Controlled Trial Evaluating Cost and Patient-Reported Outcomes

Time to reach exposure of perforators combined with time for flap elevation will be recorded during the surgical procedure.

Self-administered quality of life and outcomes questionnaire for women that undergo breast reconstruction.

Change of operative plan either prior to surgery as a result of preoperative imaging, or intra-operatively, will be recorded

Self-administered questionnaire consisting of 4 questions related to pain, pain relief, and mood.

Completed by the operating surgeon to evaluate workload based on 6 scales: mental demand, physical demand, temporal demand, performance, effort and frustration.

The costs of medical imaging and operating expenses will be calculated and compared between study groups.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Preoperative Imaging in DIEP Flap Breast Reconstruction	NCT02111239	Breast Cancer	CTA MRA	18 Years -	Sunnybrook Health Sciences Centre
Preoperative Imaging in DIEP Flap Breast Reconstruction	NCT02111239	Breast Cancer	CTA MRA	18 Years -	Sunnybrook Health Sciences Centre
Preoperative Imaging in DIEP Flap Breast Reconstruction	NCT02111239	Breast Cancer	CTA MRA	18 Years -	Sunnybrook Health Sciences Centre

Spots Global Cancer Trial Database for cta

Every month we try and update this database with for cta cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for cta

Every month we try and update this database with for cta cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for cta cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.