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lymphadenectomy including spleen-preserving No. 10 lymph node dissection will be performed for the treatment of patients assigned to this group

Laparoscopic total gastrectomy with D2 lymphadenectomy but without No. 10 lymph node dissection will be performed for the treatment of patients assigned to this group

After exclusion of T4b, bulky lymph nodes, or distant metastasis case by diagnostic laparoscopy, Laparoscopic total gastrectomy with D2 lymphadenectomy including spleen-Preserving No. 10 Lymph Node Dissection will be performed with curative treated intent. The type of reconstruction will be selected according to the surgeon's experience and anastomotic procedure is performed extracorporeally using a mini-laparotomy

D2 Lymphadenectomy including No. 10

After exclusion of T4b, bulky lymph nodes, or distant metastasis case by diagnostic laparoscopy, Laparoscopic total gastrectomy with D2 lymphadenectomy excluding spleen-Preserving No. 10 Lymph Node Dissection will be performed with curative treated intent. The type of reconstruction will be selected according to the surgeon's experience and anastomotic procedure is performed extracorporeally using a mini-laparotomy

D2 lymphadenectomy excluding No. 10

Jian Suo, Ph.D.

Yuchen Guo, Ph.D.

Jian Suo

Yuchen Guo

This study is to conduct a randomized controlled trial of two kinds of radical gastrectomy for patients with proximal gastric cancer. One is laparoscopic D2 radical total gastrectomy combined with spleen-preserving No.10 lymph node dissection , another one is laparoscopic D2 radical total gastrectomy without clearing the No. 10 lymph nodes of the spleen. We explore the effect of the two procedures on the survival of patients, as well as the surgical complications associated with the two procedures, the number of lymph node dissection, the operation time and the amount of intraoperative blood loss. Furthermore, we also want to discuss the application value of laparoscopic lymph node dissection for spleen preservation in radical gastrectomy for proximal gastric cancer.

Spleen-Preserving No. 10 Lymph Node Dissection in Gastric Cancer

Study on Laparoscopic No. 10 Lymph Node Dissection With Preservation of Spleen for Advanced Middle or Upper Third Gastric Cancer

The early postoperative complication are defined as the event observed within 30 days after surgery, while the time frame for late complication is the period from postoperative day 31th to the end of month 36th.

Recurrence patterns are classified into five categories at the time of first diagnosis: locoregional, hematogenous, peritoneal, distant lymph node, and mixed type

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Spleen-Preserving No. 10 Lymph Node Dissection in Gastric Cancer	NCT04050787	Overall Surviva...	D2 Lymphadenect... D2 lymphadenect...	18 Years - 80 Years	The First Hospital of Jilin University
Spleen-Preserving No. 10 Lymph Node Dissection in Gastric Cancer	NCT04050787	Overall Surviva...	D2 Lymphadenect... D2 lymphadenect...	18 Years - 80 Years	The First Hospital of Jilin University

Spots Global Cancer Trial Database for d2 lymphadenectomy excluding no. 10