Evaluation of the success rate of implants

Hugo De Bruyn, MD, PhD

Follow up of implants with patients receiving radiotherapy for buccopharyngeal oncology. Implants will be placed 6 weeks before start of the radiotherapy or at least 3 months after the end of the radiotherapy

Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology

University Hospital, Ghent

Musculoskeletal Diseases

Nutritional and Metabolic Diseases

All Conditions

Mouth and Tooth Diseases

Diseases and Abnormalities at or Before Birth

Rare Diseases

Osteoporosis

Tooth Loss

Anodontia

Bone Diseases

Bone Diseases, Metabolic

Metabolic Diseases

Periodontal Diseases

Mouth Diseases

Stomatognathic Diseases

Tooth Diseases

Congenital Abnormalities

Tooth Abnormalities

Stomatognathic System Abnormalities

Bone Density Conservation Agents

All Drugs and Chemicals

Denosumab

Diphosphonates

Patient with osteoporosis - antiresorptive treatment \> 4 years who have had previous tooth extraction without development of MRONJ

Patient with osteoporosis - antiresorptive treatment \> 4 years who have lost teeth due to having previous osteonecrosis of the jaw which has been successfully surgically treated and healed for at least 3 months without recurrence

Patient with osteoporosis - antiresorptive treatment \> 4 years with ongoing osteonecrosis of the jaw to be surgically treated with block resection of the lower jaw and insertion of a titanium reconstruction plate. Simultaneous insertion of dental implants, or resection of the upper jaw where there is sufficient remaining bone volume to have implants inserted simultaneously (without bone augmentation)

Patient with cancer (breast, prostate or multiple myeloma) - adjuvant dose antiresorptive treatment who have had previous tooth extraction without development of MRONJ

Patient with cancer (breast, prostate or multiple myeloma) - adjuvant dose antiresorptive treatment who have lost teeth due to having previous osteonecrosis of the jaw which has been successfully surgically treated and healed for at least 3 months without recurrence

Patient with cancer (breast, prostate or multiple myeloma) - adjuvant dose antiresorptive treatment with ongoing osteonecrosis of the jaw to be surgically treated with block resection of the lower jaw and insertion of a titanium reconstruction plate. Simultaneous insertion of dental implants, or resection of the upper jaw where there is sufficient remaining bone volume to have implants inserted simultaneously (without bone augmentation)

Cancer patient treated with high dose antiresorptive treatment who have had previous tooth extraction without development of MRONJ

Cancer patient treated with high dose antiresorptive treatment who have lost teeth due to having previous osteonecrosis of the jaw which has been successfully surgically treated and healed for at least 3 months without recurrence

Cancer patients (breast, prostate or multiple myeloma) treated with high dose antiresorptive treatment with ongoing osteonecrosis of the jaw to be surgically treated with block resection of the lower jaw and insertion of a titanium reconstruction plate. Simultaneous insertion of dental implants, or resection of the upper jaw where there is sufficient remaining bone volume to have implants inserted simultaneously (without bone augmentation)

Dental surgery in patients treated with antiresorptive medication

Dental implant surgery

Prosthetic treatment and loading of the dental implants

Prosthetic treatment

Sanne Werner Moeller Andersen, DDS

Thomas Kofod, PhD

Thomas Steengaard Kofod, PhD

Aim of the study is to examine the feasibility of dental implant insertion in patients receiving high, adjuvant and low dose \> 4 years.

The hypothesis of the present study is that dental implant therapy using submerged healing is feasible and predictable in patients receiving high, adjuvant or low dose AR for more than 4 years, as documented by clinical and radiographic signs of osseointegration after 3-4 months, sufficient implant stability for abutment connection, and implant survival rates comparable to those of healthy individuals after one year of prosthetic loading.

Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication

Defined as presence of the implant in the jaw after initial implant surgery before abutment surgery

Defined as presence of the implant at time of final prosthetics

Defined as presence of the implant 1 year after loading of the final prosthetics

Defined as presence of the implant 2 years after loading of the final prosthetics

Defined as less marginal bone loss than 1.5 mm the first year, and 0.2 mm per year thereafter at time of assessment

Defined as no exposed bone, no fistula, no radiologic sign of MRONJ

Using OHIP-14 questionnaire to evaluate oral health-related quality of life

Performance of the EORTC questionnaire for the assessment of quality of life in head and neck cancer patients

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology	NCT00313989	Dental Implants	Evaluation of t...	18 Years -	University Hospital, Ghent
Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology	NCT00313989	Dental Implants	Evaluation of t...	18 Years -	University Hospital, Ghent
Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication	NCT04741906	Missing Teeth Implants Cancer Osteoporosis	Dental implant ... Prosthetic trea...	-	Copenhagen University Hospital at Herlev
Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication	NCT04741906	Missing Teeth Implants Cancer Osteoporosis	Dental implant ... Prosthetic trea...	-	Copenhagen University Hospital at Herlev

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