Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

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Symptoms and General Pathology

Prostatic Neoplasms

Carcinoma

Pain

Genital Neoplasms, Male

Urogenital Neoplasms

Genital Diseases

Genital Diseases, Male

Urogenital Diseases

Prostatic Diseases

Male Urogenital Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Anti-Arrhythmia Agents

Channel Blockers

Anti-Inflammatory Agents

Antirheumatic Agents

Analgesics

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Lidocaine

Anesthetics, Local

Diclofenac

Sodium Channel Blockers

Diuretics, Potassium Sparing

Anti-Inflammatory Agents, Non-Steroidal

Analgesics, Non-Narcotic

Cyclooxygenase Inhibitors

Enzyme Inhibitors

Used as local aneaethetic as a part of institutional prostate biopsy protocol

Diclofenac suppository plus lidocaine gel

Lidocaine gel only

Naveed Haroon, MBBS

Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of investigation for prostate cancer in current urology practice. It is considered a minor procedure, which most of the patients tolerate, however 20% of patients refuse to undergo the redo procedure without any analgesia or anesthesia but on the other hand, some authors reveal that 65 to 90% of patients report pain ranging from mild to severe in intensity. Diclofenac is a local and systemic anti-inflammatory drug and it reduces local mediators involved in local pain.The purpose of this study is to find out the role of rectal administration of diclofenac suppositories as an adjunct to 2% xylocaine gel in alleviating intra and post procedural pain in prostatic biopsy with adequately calculated sample size and excluding the patients with contraindication to procedure or diclofenac administration as these were the shortcomings of previous studies.

Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate

Diclofenac Suppository As a Preemptive Analgesia in Ultrasound Guided Biopsy of Prostate: Randomized Controlled Trial

Aga Khan University

Resident

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate	NCT01939743	Carcinoma Prost...	Diclofenac supp... Lidocaine gel o...	51 Years - 70 Years	Aga Khan University
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate	NCT01939743	Carcinoma Prost...	Diclofenac supp... Lidocaine gel o...	51 Years - 70 Years	Aga Khan University

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