Neoplasms

Digestive System Diseases

All Conditions

Colorectal Neoplasms

Colonic Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Rectal Diseases

Herbal and Botanical

All Drugs and Chemicals

Cola

Patients will receive mailed FIT kits in a box with differentiated packaging

Differentiated Box

Patients will receive mailed FIT in a standard mailing envelope

Standard Mail

Patients will receive a series of up to 3 texts explaining the importance of colon cancer screening and prompts to complete the mailed FIT.

Text

Patients will not receive text messaging explaining the importance of colon cancer screening or prompts to complete the mailed FIT.

No Text

Patients will receive a mailed letter reminder to complete their FIT kit if not resulted by 1 month from initial outreach.

Reminder

Patients will not receive any mailed letter reminder to complete their FIT kit.

No Reminder

Shivan Mehta, MD

This project aims to evaluate different approaches to increase colorectal cancer screening among primary care patients at Penn Medicine through a centralized screening outreach program. In a pragmatic trial, we will evaluate different approaches to increase response rate to mailed fecal immunochemical test (FIT) kits among eligible patients, including differentiated packaging, sending text reminders, and personalized reminders.

While colonoscopy procedures are recommended by guidelines for early detection of colorectal cancer, colonoscopy access remains limited due to delays in screening due to the pandemic and capacity issues. In this project, we will evaluate different ways of reaching out to eligible patients to encourage them to participate in colorectal cancer screening using fecal immunochemical testing (FIT). In a mailed FIT outreach campaign, we will compare user friendly packaging, text messaging, and personalized reminders to standard outreach with the goal of increasing colorectal cancer screening uptake.

Mailed FIT Outreach 2022

Pragmatic Trial of Behavioral Interventions to Increase Response to Mailed FIT Outreach

Percent of patients who complete any CRC screening

Percent of patients with FIT+ results that schedule a colonoscopy

Percent of patients with FIT+ results that complete a diagnostic colonoscopy

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Mailed FIT Outreach 2022	NCT05341622	Colorectal Canc... Colon Cancer	Differentiated ... Standard Mail Text No Text Reminder No Reminder	50 Years - 74 Years	Abramson Cancer Center at Penn Medicine
Mailed FIT Outreach 2022	NCT05341622	Colorectal Canc... Colon Cancer	Differentiated ... Standard Mail Text No Text Reminder No Reminder	50 Years - 74 Years	Abramson Cancer Center at Penn Medicine
Mailed FIT Outreach 2022	NCT05341622	Colorectal Canc... Colon Cancer	Differentiated ... Standard Mail Text No Text Reminder No Reminder	50 Years - 74 Years	Abramson Cancer Center at Penn Medicine

Spots Global Cancer Trial Database for differentiated box