Nutritional and Metabolic Diseases

Symptoms and General Pathology

All Conditions

Gland and Hormone Related Diseases

Neoplasms

Obesity

Thyroid Diseases

Weight Loss

Thyroid Neoplasms

Body Weight

Body Weight Changes

Endocrine System Diseases

Endocrine Gland Neoplasms

Head and Neck Neoplasms

In the experimental group (digital lifestyle management group), 54 patients are randomly assigned to the digital lifestyle management group. The patients use this application for the first 4 months with Noom applications with 1:1 personalized coaching intervention, and then, use this app by self-help program without coaching intervention. In order to monitor the psychological state of the patients, all the patients are given daily assessment online questionnaires and additional questionnaires to evaluate the quality of life at the baseline, 4 months, and 6 months after surgery. To assess the nutritional status of the patients, we collect blood laboratory data, bioimpedance analysis for each visit.

In the control group (Non-digital lifestyle management group), 26 patients are randomly assigned to the control group (Non-digital lifestyle management group). The patients follow conventional postoperative care protocol after total thyroidectomy for thyroid cancer without using Noom application. All patients are given questionnaires to evaluate the quality of life at the baseline, 4 months, and 6 months after surgery. To assess the nutritional status of the patients, we collect blood laboratory data, bioimpedance analysis for each visit.

Digital lifestyle management for Weight Loss Control after Thyroidectomy

Digital lifestyle management

Kyu Eun Lee

JungHak Kwak

Kyu Eun Lee, Ph.D

Kyu Eun Lee, MD, Ph.D

Thyroid hormones play an important role in the regulation of the body's metabolism. But the relationship between thyroid hormone status and the basal metabolism rate is not absolute. Because thyroid hormone function is not the only factor of control the metabolism and it can be influenced by various factors such as physical activity and diet.

Weight change after thyroidectomy is one of the concerns for thyroid cancer patients. The evidence on the bodyweight changes following thyroidectomy has not been established well. Being overweight and obese can increase the risk of developing many potential health problems, such as heart disease, diabetes, high blood pressure, and malignant disease.

Recently, digital health care technology has been developed and applied for medical purposes in many clinical practices. Digital Lifestyle Management is one of the strategies that can be helpful for the obese to control their body weight by lifestyle modification. It provides comprehensive, multifactorial, intensive interventions which are delivered via the digital health care mobile service Noom application.

The aim of this study is to evaluate the efficacy of digital lifestyle management on body weight and quality of life after total thyroidectomy in thyroid cancer patients by using the digital health care Noom application.

The present study is a prospective randomized control trial. A total of 80 patients who underwent total thyroidectomy for thyroid cancer is included. Fifty-four patients are randomly assigned to the digital lifestyle management group and the other 26 patients are assigned to the non-digital lifestyle management group.

In the experimental group (digital lifestyle management group), the patients will use this application for the first 4 months with Noom applications with 1:1 personalized coaching intervention, and then, use this app by self-help program without coaching intervention. The digital lifestyle management program will record the patient's meals, exercise, steps taken, reading articles, and give feedback to each patient. In order to monitor the psychological state and quality of life of the patients, online questionnaires will be provided.

In the control group (non-digital lifestyle management group), the patients will get the conventional postoperative care protocol without using the Noom application. To investigate the weight change and quality of life, variables are collected at baseline, 4 months, and 6 months after surgery.

Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients

Validating Efficacy for Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients

Change from baseline weight at 4 months and 6 months after surgery

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Korean Obesity Quality of Life (KOQOL)

* Range: 4-60
* Higher scores: impaired QOL

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# World Health Organization Quality of Life - Brief Form (WHOQOL-Bref)

* Range: 0-100
* Higher scores: higher QOL

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Pittsburgh Sleep Quality Index (PSQI)

* Range: 0-21
* Lower scores: a healthier sleep quality

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Korean-Beck Depression Inventory-II (K-BDI-II)

* Range: 0-63
* Higher scores: Depression

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# State-Trait Anxiety Inventory (STAI)

* Range: 20-80
* Higher scores: anxiety

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Rosenberg Self-Esteem Scale (RSES)

* Range: 0-30
* Higher scores: lower self-esteem

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Body Shape Questionnaire (BSQ-8C)

* Range: 8-48
* Higher values: body dissatisfaction

Change from baseline results of questionnaires at 4 months and 6 months after surgery

# Dutch Eating Behaviour Questionnaire (DEBQ)

* Range: 33-165
* Higher scores: the eating behavior

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients	NCT05126706	Weight Change, ...	Digital lifesty...	19 Years - 70 Years	Seoul National University Hospital
Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients	NCT05126706	Weight Change, ...	Digital lifesty...	19 Years - 70 Years	Seoul National University Hospital

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