Neoplasms

Nervous System Diseases

All Conditions

Brain Neoplasms

Central Nervous System Neoplasms

Nervous System Neoplasms

Brain Diseases

Central Nervous System Diseases

Participants with newly diagnosed intracranial malignant tumors, from whom blood samples will be collected.

Participants with newly diagnosed benign central nervous system disorders, from whom blood samples will be collected.

Participants without known presence of malignancies or certain benign diseases, from whom blood samples will be collected.

Blood collection and early detection testing

early detection test

Hongbo Guo, MD, Ph.D

Boyang Liu, MD

Hongbo Guo, MD,Ph.D

ASCEND-BRAIN is a prospective, observational study aimed at early-detection of intracranial tumors by combined assays of cfDNA methylation and other biomarkers. The study will enroll approximately 358 participants including intracranial malignant tumors, patients with benign disorders of central nervous system and healthy participants.

AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors

Assessment of Early Detection Based on Liquid Biopsy in Intracranial Tumors: a Prospective Observational Study

Guangzhou Burning Rock Dx Co., Ltd.

Zhujiang Hospital

Blood and Lymph Conditions

Immune System Diseases

Rare Diseases

Lymphoma

Neoplasms by Histologic Type

Lymphoproliferative Disorders

Lymphatic Diseases

Immunoproliferative Disorders

Lymphosarcoma

Participants with new diagnosis of lymphoid malignancies, from whom blood samples will be collected.

Participants with new diagnosis of benign lymphoid diseases, from whom blood samples will be collected.

Huiqiang Huang, Ph.D

Yan Gao, Ph.D

Yan Gao

ASCEND-LYM is a prospective, multi-center, observational study aimed at detecting early stage lymphoma and constrcuting prognostic model by combined assays of cfDNA methylation and other biomarkers. The study will enroll approximately 493 participants including lymphoid malignancies and benign diseases.

Assessment of Early-detection Based on Liquid Biopsy in Lymphoid Malignancies

Assessment of Early-detection Based on Liquid Biopsy in Lymphoid Malignancies: a Multi-center Prospective Observational Study

Sun Yat-sen University

chief physician

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors	NCT05679089	Intracranial Tu...	early detection...	40 Years - 75 Years	Zhujiang Hospital
AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors	NCT05679089	Intracranial Tu...	early detection...	40 Years - 75 Years	Zhujiang Hospital
Assessment of Early-detection Based on Liquid Biopsy in Lymphoid Malignancies	NCT05275036	Lymphoma	early detection...	40 Years - 75 Years	Sun Yat-sen University
Assessment of Early-detection Based on Liquid Biopsy in Lymphoid Malignancies	NCT05275036	Lymphoma	early detection...	40 Years - 75 Years	Sun Yat-sen University

Spots Global Cancer Trial Database for early detection test