Symptoms and General Pathology

All Conditions

Neoplasms

Musculoskeletal Diseases

Hemorrhage

Postoperative Hemorrhage

Bone Neoplasms

Bone Diseases

Postoperative Complications

Coagulants

All Drugs and Chemicals

Tranexamic Acid

Hemostatics

Fibrin Tissue Adhesive

Antifibrinolytic Agents

Tranexamic acid, 1g intra-articular before closing the surgery wound

One intra-articular dose of fibrin glue (Evicel 5mL) before closing the wound surgery

1g intra-articular before closing the wound surgery

5mL intra-articular before closing the wound surgery

Fibrin glue

Coagulation blood from vessels by means of a electrocautery

Electrocauterization

Ana Peiró, MD

Massive bone tumour resection is often associated with important postoperative bleeding. This may determine systemic (anaemia), as well as local complications (wound healing, seroma, haematoma).

The objective of this study is to determine whether the use of topical tranexamic acid or topical Evicel® will reduce the perioperative bleeding comparing it with usual haemostasis.

Postoperative Bleeding Prevention in Massive Bone Tumour Resection

Postoperative Bleeding Prevention in Massive Bone Tumour Resection: a Multicentric, Randomized, Parallel, Controlled Trial to Assess the Efficacy of Tranexamic Acid Versus Evicel® and Usual Haemostasis

The blood loss will be collected by the drainage system and quantified in mL.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Postoperative Bleeding Prevention in Massive Bone Tumour Resection	NCT02153593	Blood Loss Bone Tumour	Tranexamic Acid Fibrin glue Electrocauteriz...	18 Years -	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postoperative Bleeding Prevention in Massive Bone Tumour Resection	NCT02153593	Blood Loss Bone Tumour	Tranexamic Acid Fibrin glue Electrocauteriz...	18 Years -	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Spots Global Cancer Trial Database for electrocauterization