Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Endometrial Neoplasms

Uterine Neoplasms

Genital Neoplasms, Female

Urogenital Neoplasms

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Endometrial cancer radical surgery to be administered in this arm.

Fertility-sparing surgery to be administered in this arm.

Ovarian preservation surgery to be administered in this arm.

Take hysterectomy and bilateral adnexectomy.

endometrial cancer radical surgery

Take endometrectomy , preserve uterus and bilateral ovaries.

fertility-sparing surgery

Take hysterectomy,preserve bilateral ovaries.

ovarian preservation surgery

Min Wang, PHD.

YiSi Liu

Min Wang, PHD

Through multicenter, prospective, randomized, controlled clinical studies comparing different treatment options (fertility-sparing surgery and ovarian preservation surgery and radical surgery)therapeutic efficacy, safety and quality of life of patients, exploration of the best strategies and risks for the treatment of early endometrial cancer, and promotion and application.

Patients eligible for enrollment are selected and divided into three groups randomly, including fertility group,ovarian preservation group and endometrial cancer radical surgery group. Take interventions including fertility preservation surgery,ovarian preservation surgery and endometrial cancer radical surgery for patients in different groups respectively. Compare therapeutic efficacy, safety and quality of life of patients to evaluate three treatment and explore the best treatment for clinical application.

The Multicentic Trial in Fertility-sparing Treatment and Ovarian Preservation Management for Early Endometrial Cancer

The Randomized Multicentic Prospective Controlled Trial in Fertility-sparing Treatment and Ovarian Preservation Management for Early Endometrial Cancer

calculate the time from patients enter the group to death

measure the ovarian volume dynamically by ultrasonography

measure the endocrine function(hormone level) dynamically by blood detection

calculate the time from patients enter the group to tumor progression

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
The Multicentic Trial in Fertility-sparing Treatment and Ovarian Preservation Management for Early Endometrial Cancer	NCT03804463	Endometrial Can...	endometrial can... fertility-spari... ovarian preserv...	21 Years - 65 Years	Shengjing Hospital
The Multicentic Trial in Fertility-sparing Treatment and Ovarian Preservation Management for Early Endometrial Cancer	NCT03804463	Endometrial Can...	endometrial can... fertility-spari... ovarian preserv...	21 Years - 65 Years	Shengjing Hospital

Spots Global Cancer Trial Database for endometrial cancer radical surgery