Gland and Hormone Related Diseases

All Conditions

Neoplasms

Rare Diseases

Thyroid Diseases

Carcinoma

Thyroid Neoplasms

Thyroid Cancer, Papillary

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Endocrine System Diseases

Endocrine Gland Neoplasms

Head and Neck Neoplasms

Adenocarcinoma

Adenocarcinoma, Papillary

Papillary Thyroid Carcinoma

Anti-Infective Agents

All Drugs and Chemicals

Blood Substitutes

Micronutrients

Povidone-Iodine

Povidone

Iodine

Cadexomer iodine

Parathyroid Hormone

Patients in the retro-auricular single-site endoscopic thyroidectomy (RASSET) group will receive endoscopic thyroid lobectomy and central lymph node dissection.

Patients in the Transoral Endoscopic Thyroidectomy Vestibular Approach group will receive endoscopic thyroid lobectomy and central lymph node dissection.

Patients in the Transareola Endoscopic Thyroidectomy group will receive endoscopic thyroid lobectomy and central lymph node dissection.

The strap muscles and the sternocleidomastoid muscle were separated. Upper parathyroid and lower parathyroid glands were identified and preserved. The recurrent laryngeal nerve (RLN) was identified，A lobe of thyroid specimen and central lymph nodes were dissected.

Retro-Auricular Single-Site Endoscopic Thyroidectomy

The patient was placed in a supine position with slight neck extension under nasotracheal intubation. The mouth was garbled with povidone iodine before surgery. Three laparoscopic ports (a 10- to 15-mm port at midline and two 5-mm ports at the lateral junction between the canine and first premolar teeth)were inserted under the lower lip at the oral vestibular area.The strap muscleswere separated in the midline to expose the thyroid and trachea. The recurrent laryngeal nerve (RLN) was identified at the insertion to the larynx, then followed downandparallel tothe trachea inferiorly.

Transoral Endoscopic Thyroidectomy Vestibular Approach

The patient was in supine position. Incision was made inside the right areola and a 10mm puncture device was placed, subcutaneous separation rod was used to separate the space, and a 30° endoscope was introduced, puncture device was placed in a 5mm incision on the left areola, ultrasonic knife free flap was used, subcutaneous separation space was placed in the upper sternal segment, and a 5mm puncture device was placed outside the right areola. The anterior cervical flap was further dissociated to establish a space. The median cervical line was cut to cut off the isthmus of the thyroid, and the tracheal fascia ligament of the thyroid was separated and the nerve was exposed to protect the nerves. Then remove the lobe of thyroid and central lymph nodes

Transareola Endoscopic Thyroidectomy

Dian Ouyang

The goal of this retrospective study is to compare the safety and efficiacy of endoscopic thyroidectomy via retro-auricular single-site approach, transoral endoscopic thyroidectomy vestibular approach and transareola approach.

Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola

Single-center, Retrospective Study of Retro-Auricular Single-Site Endoscopic, Transoral Endoscopic Thyroidectomy Vestibular Approach and Transareola Endoscopic Thyroidectomy in Patients With Early Stage Papillary Thyroid Carcinoma

the level of CRP before and after operation

The volume of blood loss during operation

Postoperative specimen Postoperative specimen Postoperative specimen Postoperative specimen the number of lymph nodes in postoperative specimens

Sun Yat-sen University

Clinical Professor

Patients who met the inclusion criteria were selected for a conventional open surgery procedure for a conventional neck incision for thyroid surgery.

Patients who met the inclusion criteria were selected to undergo thyroid surgery via endoscopic thyroidectomy

Patients who met the inclusion criteria chose the Da Vinci robot for thyroid surgery.

conventional open surgery

endoscopic thyroidectomy

robotic thyroidectomy

bo wang, md

wenxin zhao, md

Wen-xin ZHAO, MD

Bo WANG, MD

Comparison of endoscopic thyroidectomy, robotic thyroidectomy and conventional open surgery, the safety of the operation, the timing of the operation and the complications.

With the further development of endoscopic technique, thyroid surgery of the robot has emerged, which may become a trend of endoscopic technology due to its convenience and accuracy.In this study, the advantages and disadvantages of endoscopic thyroidectomy and robotic thyroid surgery were compared, and the experience in the transition stage of thyroid surgery in robotic and endoscopic thyroidectomy was summarized.

Comparison Between Robotic, Endoscopic and Traditional Open Surgery in Thyroidectomy

From the Endoscope to the Robot, the Initial Experience of Robotic Thyroidectomy is Summarized

the number of recurrent laryngeal nerve palsy

The satisfaction with cosmetic outcomes was analyzed quantitatively using a scoring system that ranged from 1 to 4(1, extremely; 2, fairly; 3, normal; 4: not at all) that was rated by patients at the outpatient clinic 2 months after the operation.

Fujian Medical University

clinical professor

total thyroidectomy via endoscopic approach and that convert to open procedure

thyroidectomy

MIng QIU, Dr.

Wei ZHANG, Dr.

Chengxiang SHAN, master

Daozhen JIANG, Dr.

Ming QIU, Dr.

Endoscopic thyroidectomy has been used to treat thyroid diseases in China. However, whether this technique is rational to treat thyroid carcinoma is still in controversy. The diagnosis of thyroid carcinoma is predominantly made according to intra-operative frozen section pathological examination in China. In this research, the investigators want to compare clinical index (blood loss, operation duration, number of lymph nodes dissected, complication rates, etc) between patients underwent endoscopic thyroidectomy ( total thyroidectomy) and those underwent conversion to open procedure. The investigators want to evaluate the technical feasibility of endoscopic thyroidectomy for treating thyroid carcinoma.

intra-operative diagnosis of thyroid carcinoma is usually considered the indication of conversion to open surgery. with accumulation of experience of endoscopic thyroidectomy, the investigators want to evaluate the technical feasibility, completeness and safety of endoscopic thyroidectomy.

Feasibility of Endoscopic Thyroidectomy for Thyroid Carcinoma

Comparison of Effectiveness and Safety of Thyroidectomy for Thyroid Carcinoma in Patients Undergo Endoscopic Surgery and Those Receive Conversion

Second Military Medical University

Minimally Invasive Surgical Center, Changzheng Hospital

3 trocars are needed. two in the circumareolar region and one in the parasternal region. the dissection area begins from the trocar site and extends to the neck.

the dissection is reduced by creating a long tunnel from the trocar site and the dissection area confined in the upper chest wall and in the neck.

endoscopic thyroidectomy via the breast approach. the difference between two arms is in the subcutaneous dissection area.

wei zhang, MD

ming qiu, MD

cheng-xiang shan, MD

sheng liu, MD

The purpose of this study is to investigate whether reduced subcutaneous dissection area could offer patients more clinical benefits.

To create a working place in the chest wall is an inevitable step of endoscopic thyroidectomy. Large subcutaneous area was considered a drawback of endoscopic thyroidectomy. The purpose of this study is to investigate whether subcutaneous dissection area has influence on clinical outcome of endoscopic thyroidectomy, such as post-operative pain, complication rate and post-operative discomfort.

Impact of Dissection Area on the Clinical Outcome of Endoscopic Thyroidectomy

Clinical Benefits of Reduced Subcutaneous Dissection in Endoscopic Thyroidectomy

24hs after operation, post-operative pain is evaluated by VAS(visual analoge scale)

record how many patients had adverse effects(eg. bruise, seroma, hematoma, hoarseness,hypocalciemia)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola	NCT05760690	Papillary Thyro...	Retro-Auricular... Transoral Endos... Transareola End...	18 Years - 70 Years	Sun Yat-sen University
Comparison Between Robotic, Endoscopic and Traditional Open Surgery in Thyroidectomy	NCT03454477	Endoscopy Robotics Thyroidectomy Papillary Thyro...	conventional op... endoscopic thyr... robotic thyroid...	18 Years - 70 Years	Fujian Medical University
Feasibility of Endoscopic Thyroidectomy for Thyroid Carcinoma	NCT00993837	Thyroid Carcino...	thyroidectomy	18 Years - 45 Years	Second Military Medical University
Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola	NCT05760690	Papillary Thyro...	Retro-Auricular... Transoral Endos... Transareola End...	18 Years - 70 Years	Sun Yat-sen University
Impact of Dissection Area on the Clinical Outcome of Endoscopic Thyroidectomy	NCT01338597	Thyroid Tumor	endoscopic thyr...	18 Years - 50 Years	Second Military Medical University

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