Neoplasms

Digestive System Diseases

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Biliary Tract Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Biliary Tract Diseases

Gastrointestinal Diseases

patients receiving enteral nutrition (EN) after surgery

patients receiving parenteral nutrition (PN)

parenteral nutrition supplements

enteral nutrition supplements

mixed nutrition supplements

Sherzad Davanov, MD

A comprehensive comparative analysis of the effectiveness of isolated enteral, isolated parenteral and mixed type of nutritional support in the early postoperative period in patients after operations performed on the malignant neoplasms of hepatico-pancreatico-duodenal zone.

A prospective, longitudinal, parallel study and retrospective analysis of the results of treatment of 91 patients with malignant tumors of the hepatico-pancreato-duodenal zone who underwent the following operations:

1. resection of various segments of the liver;
2. hemihepatectomy;
3. transhepatic drainage of the right and left hepatic duct;
4. bypass gastroenteroanastomosis or cholecystenteroanastomosis with interintestinal enteroenteroanastomosis according to Brown;
5. gastro-pancreato-duodenal resection;
6. corpore-caudal resection of the pancreas with splenectomy.

The first group (n=31) included patients who received enteral nutrition (EN) after surgery. The second group (n=30) included patients who received parenteral nutrition (PN) and the third group (n=30) who received mixed nutrition (MN), as a variation of the partial parenteral nutrition technique, in the early postoperative period.

Some nutritional status indicators available for determination at the Oncology Clinic were assessed - body mass index (weight measurements were carried out before surgery, on the 5th, 10th and 15th days), basal metabolic rate (calculated using the Harris-Benedict equation, based on anthropometric data of the patient (gender, age, weight and height).), laboratory parameters: blood hemoglobin, lymphocytes, total protein, serum albumin, serum transferrin, total bilirubin and direct, alanine aminotransferase (ALT), aspartate aminotransferase (AST), which are related to the traditional method for assessing nutritional status

prospective, longitudinal, parallel study

Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone

Nutritional Support for Patients Operated on for Malignant Tumors of the Hepatico-pancreato-duodenal (HPD) Zone in the Early Postoperative Period

Variables of Body mass index measured by Canadian Guidelines for Body Weight Classification in Adults

basal metabolic rate according to the Harris-Benedict equation

Blood biochemical analysis: total protein in g/L

Blood biochemical analysis: serum albumin in g/L

Blood biochemical analysis: serum transferrin in g/L

Blood biochemical analysis: total bilirubin in mmol/L

Blood biochemical analysis: direct bilirubin in mmol/L

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone	NCT06397430	Nutritional Sup... Hepato-Biliary ... Postoperative	parenteral nutr... enteral nutriti... mixed nutrition...	20 Years - 75 Years	Karaganda Medical University
Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone	NCT06397430	Nutritional Sup... Hepato-Biliary ... Postoperative	parenteral nutr... enteral nutriti... mixed nutrition...	20 Years - 75 Years	Karaganda Medical University

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