Symptoms and General Pathology

All Conditions

Neoplasms

Digestive System Diseases

Polyps

Colonic Neoplasms

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Adjuvants, Anesthesia

Analgesics

Psychotropic Drugs

Anesthetics

Fentanyl

Midazolam

Propofol

Hypnotics and Sedatives

Anesthetics, Intravenous

Anesthetics, General

Anti-Anxiety Agents

GABA Modulators

Neurotransmitter Agents

Analgesics, Opioid

Narcotics

Patients in the treatment arm will be given propofol only when having a colonoscopy.

Patients in the control arm will receive only the standard of care medications, fentanyl and midazolam when having a colonoscopy.

The intervention is to use propofol as anesthesia during a colonoscopy.

The control is to use standard of care anesthesia, fentanyl and midazolam, during a colonoscopy.

Fentanyl Plus Midazolam

Anantha Padmanabhan, MD

The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.

Outpatient colonoscopies are very common, indicated for various reasons, and are more commonly performed in outpatient surgery or endoscopy centers. There is an increase in the use of propofol for sedation because of the short duration of action and quick turn around time. Propofol has been studied extensively for safety and efficacy but patient satisfaction and preference with use has not been well documented in prospective, randomized setting. In the context of the recent changes in healthcare reimbursement where patient satisfaction is becoming an important metric providing data that could improve patient satisfaction is needed.

Patients who presented for a colonoscopy with the Principal Investigator were approached to participate in the study. After obtaining consent the patients were randomized to anesthesia with propofol or control without propofol per random number tables provided by the statistician. The anesthesiologist or nurse anesthetist were asked to remove the paper with the assignment from the envelope to determine which medications to give the patient. Pre-op, intra-op, and post-op data were collected by registered nurses blinded to the anesthetic. The day one follow-up phone call was made by the resident who was blinded to the anesthetic. Data were collected in the pre-op, intra-op, and post-op areas by the researchers who were blinded to the medications used.

Patient Satisfaction With Propofol for Out Patient Colonoscopy

Patient Satisfaction With Propofol for Out Patient Colonoscopy: A Prospective, Randomized, Double-Blind Study

Satisfaction assessed using self-developed questionnaire.

Mount Carmel Health System

Patients in the treatment arm will be given propofol only when having a colonoscopy.

Propofol: The intervention is to use propofol as anesthesia during a colonoscopy.

Patients in the control arm will receive only the standard of care medications, fentanyl and midazolam when having a colonoscopy.

Fentanyl Plus Midazolam: The control is to use standard of care anesthesia, fentanyl and midazolam, during a colonoscopy.

Fentanyl Plus Midazolam Only

Total

The age of the participant in completed years.

Age, Continuous

Sex: Female, Male

Patients scheduled for an outpatient colonoscopy at a single ambulatory surgery center.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Patient Satisfaction With Propofol for Out Patient Colonoscopy	NCT02937506	Colon Cancer IBS Polyps	Propofol Fentanyl Plus M...	18 Years -	Mount Carmel Health System
Patient Satisfaction With Propofol for Out Patient Colonoscopy	NCT02937506	Colon Cancer IBS Polyps	Propofol Fentanyl Plus M...	18 Years -	Mount Carmel Health System

Spots Global Cancer Trial Database for fentanyl plus midazolam