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Neonatal Ovarian Cyst

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Fetal ovarian cyst aspiration performed as soon as possible

Fetal ovarian cyst aspiration performed under ultrasound guidance and maternal local anesthesia

Fetal ovarian cyst aspiration

Franck Perrotin, MD--PhD

The purpose of this study is to determine whether prenatal ovarian cyst aspiration is effective and safe to prevent perinatal ovarian torsion.

With the widespread use of routine sonography during pregnancy, the incidence of fetal ovarian cysts detected in utero has increased in the past decades. However

Effect of Fetal Ovarian Cyst Aspiration to Prevent Torsion

Comparison Between Abstention and Intrauterine Aspiration in the Treatment of Anechoic Fetal Ovarian Cysts to Prevent Ovarian Torsion

University Hospital, Tours

Pr Franck Perrotin

Patients will choose how they wish to complete the Pubertal Course Questionnaire: electronically (web link), on paper, by telephone, or face-to-face at a follow-up consultation.

Questionnaire

Catherine PIENKOWSKI, MD

This study is based on pubertal surveillance of fetal ovarian cysts (KOF). Fetal ovarian cysts (KOF) detected during fetal ultrasound examinations occur during the 3rd trimester of pregnancy and are of unknown cause.

These cysts are functional in the vast majority of cases and are therefore likely to disappear spontaneously, but they may become complicated before regressing. Apart from complication, the natural evolution of these cysts, which are said to be "simple" because they are liquid on ultrasound, is towards regression in the first months of neo-natal life.

Surveillance during the 1st year of life showed that simple cysts regressed during the 1st trimester. In the case of complicated cysts, oophorectomy was necessary in 9 cases. In the 1-year follow-up, the ovarian recovery rate was significantly different depending on the appearance of the cyst (p\<0.0001); 60 ovaries out of 89 homolateral to the cyst were follicular, of which 48/49 (98%) were carriers of fluid cysts and 12/40 (30%) were initially heterogeneous. The origin of these cysts is unknown, the ovary is again physiologically stimulated during the onset of puberty. No series in the literature gives the long-term ovarian prognosis for these patients. We wish to evaluate the pubertal evolutionary profile of patients followed at the University Hospital for KOF. The data collected concerning puberty (age of menses) will be examined in relation to the age of menses in the siblings and in the mother, as well as to the data in the literature on the age of the first menses in France.

Pubertal Evolutionary Profile of Children Monitored for Fetal Ovarian Cyst

Age of onset of first menstruation defined with one decimal place (year and month).

Average age of maternal and sister menstruation.

Homo and contralateral ovarian volumes at the cyst.

Presence or not of follicles on both ovaries.

Percentage of girls with clinical signs of hyperandrogenism or elevated testosterone levels.

follicle stimulating hormone (FSH) levels

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Effect of Fetal Ovarian Cyst Aspiration to Prevent Torsion	NCT00222066	Ovarian Cyst Ultrasonography...	Fetal ovarian c...	18 Years - 40 Years	University Hospital, Tours
Pubertal Evolutionary Profile of Children Monitored for Fetal Ovarian Cyst	NCT04526392	Fetal Ovarian C...	Questionnaire	8 Years - 18 Years	University Hospital, Toulouse
Pubertal Evolutionary Profile of Children Monitored for Fetal Ovarian Cyst	NCT04526392	Fetal Ovarian C...	Questionnaire	8 Years - 18 Years	University Hospital, Toulouse
Effect of Fetal Ovarian Cyst Aspiration to Prevent Torsion	NCT00222066	Ovarian Cyst Ultrasonography...	Fetal ovarian c...	18 Years - 40 Years	University Hospital, Tours

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