Neoplasms

Digestive System Diseases

All Conditions

Colonic Neoplasms

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

All Drugs and Chemicals

Nicotine

Email outreach + active choice + financial incentive

Subjects will receive an email describing the importance of colorectal cancer screening and that s/he has been selected to participate in this VIP concierge service.

Email outreach

S/he will receive the ability to pre-commit and choose from 3 different appointment slots by clicking directly on the email.

Active choice

The participant will receive the offering of $100 if s/he follows through with screening colonoscopy.

Financial incentive

Shivan Mehta, MD

This is an RCT aimed at testing different population-based approaches to increasing colorectal cancer screening through email outreach, including usual email communication, active choice, and active choice + financial incentive.

This is an RCT aimed at testing different population-based approaches to increasing colorectal cancer screening. The investigators will randomize a cohort of employees between the ages of 50-64 to 3 arms of email communications: a.) Usual email communication; b.) Active choice- usual care + the ability to pre-commit directly through a web form; c.) Financial incentive- usual care + active choice + financial incentive for completion.

Behavioral Economic Approaches to Increase Colorectal Cancer Screening

The percentage of participants who follow through with screening colonoscopy.

The percentage of participants who respond to the email (arm 2 and 3).

The percentage of participants who schedule a procedure.

University of Pennsylvania

Infections

Virus Diseases

Papilloma

Neoplasms, Squamous Cell

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Vaccines

Staff in clinics randomized to this arm will receive an intervention called Announcement Approach Training (AAT). This training is designed to improve communication about HPV vaccination.

Staff in clinics randomized to this arm will receive the Announcement Approach Training and a clinic-level financial incentive program with a monthly data feedback report to increase HPV vaccine uptake.

Clinics will host an Announcement Approach Training (AAT) workshop. A trained facilitator will use a standard script and slides to deliver workshop in-person or over Zoom; clinical staff who are unavailable will take the workshop later on their own.

Communication training

Clinics will host an AAT workshop, as in the other trial arm. Clinics in the intervention arm will then receive a 12-month clinic-level financial incentive program with predetermined targets for HPV vaccine initiation rates (5%, 10%, and 30% increases from baseline). Clinics will be notified of their HPV vaccination rates though a monthly, automated report. Clinic achievement will be assessed and incentives will be paid out to clinics monthly. Incentives will be tiered based on target and sized based on the number of clinic providers. For reaching the highest tier of 30%, clinics will receive an aggregate of $1000 per provider.

financial Incentive

Kathryn R Brignole, MSc

Justin G Trogdon, PhD

This trial will look at the impact of clinic-level financial incentives to improve provider communication and increase HPV vaccine uptake. Some clinics will receive communication training. Other clinics will receive the same training and a clinic-level financial incentive program with a monthly data feedback report to increase HPV vaccine uptake.

The researchers will conduct a cluster randomized control trial. This trial will look at the impact of clinic-level financial incentives to improve provider communication and increase HPV vaccine uptake. The recruitment goal for the trial is 34 clinics in healthcare systems, including 9 rural-serving clinics. The researchers will randomize clinics using simple randomization (1:1). Some clinics will receive communication training. Other clinics will receive the same training and a clinic-level financial incentive program with a monthly data feedback report to increase HPV vaccine uptake. The researchers will use medical record data to compare changes in HPV vaccination among children ages 9-12. Clinics will be followed for 24 months. The study will engage clinical staff. Researchers will not have direct contact with children or their families.

1:1 ratio control and intervention arm randomized controlled trial

Impact of Financial Incentives

The Impact of Clinic-level Financial Incentives on HPV Vaccine Communication and Uptake

Proportion of unvaccinated children who initiate the HPV vaccine series between baseline and 12-month follow-up, among those who were ages 9-12 at baseline.

Proportion of unvaccinated children who initiate the HPV vaccine series between 13- and 24-month follow-up, among those who were ages 9-12 at 13 months.

Proportion of unvaccinated children who complete the HPV vaccine series between baseline and 12-month follow-up, among those who were ages 9-12 at baseline.

Proportion of unvaccinated children who complete the HPV vaccine series between 13- and 24-month follow-up, among those who were ages 9-12 at 13 months.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Behavioral Economic Approaches to Increase Colorectal Cancer Screening	NCT02660671	Cancer of the C...	Email outreach Active choice Financial incen...	50 Years - 64 Years	University of Pennsylvania
Impact of Financial Incentives	NCT05744960	Human Papilloma...	Communication t... financial Incen...	9 Years - 12 Years	UNC Lineberger Comprehensive Cancer Center

Spots Global Cancer Trial Database for financial incentive