Neoplasms

All Conditions

Skin and Connective Tissue Diseases

Rare Diseases

Sarcoma

Sarcoma, Ewing

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Osteosarcoma

Neoplasms, Bone Tissue

Neoplasms, Connective Tissue

Soft Tissue Sarcoma

Ewing Sarcoma

All Drugs and Chemicals

Antineoplastic Agents

Reproductive Control Agents

Vaccines

Fludarabine

Fludarabine phosphate

Melphalan

Busulfan

Levonorgestrel

Antineoplastic Agents, Alkylating

Alkylating Agents

Immunosuppressive Agents

Immunologic Factors

Subjects will receive the vaccine, Busulfan and Melphalan.

If subject have already received a stem cell transplant using Busulfan and Melphalan, they will receive Clysophosohamide and Fludarabine.

allogeneic stem cell transplantation

Clyclophosphamide

Fludarabina

Kenneth Lucas, M.D.

The purpose of this study is to examine the toxicity of using allogeneic stem cell transplantation for treatment of subjects with relapsed or refractory Ewing Sarcoma (ES). Donors will consist of either Human Leukocyte Antigen identical (HLA)or 9/10 (A, B, C, DR, DQ \[A, B, C, are Class I markers for HLA and DR and DQ are Class II markers for Matching for Transplant for Donors to match with recipient\]) matched related or unrelated donors. Specifically, we will examine:

* The toxicity of allogeneic stem cell transplant (SCT) in this patient population, as related to incidence of grade 3-4 acute Graft Verse Host Disease (GVHD).
* The incidence of transplant related mortality at 100 days.

A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma

University of Louisville

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma	NCT01969942	Ewing Sarcoma	allogeneic stem... Clyclophosphami... Fludarabina Busulfan Melphalan	- 30 Years	University of Louisville
A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma	NCT01969942	Ewing Sarcoma	allogeneic stem... Clyclophosphami... Fludarabina Busulfan Melphalan	- 30 Years	University of Louisville

Spots Global Cancer Trial Database for fludarabina

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Spots Global Cancer Trial Database for fludarabina

Every month we try and update this database with for fludarabina cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for fludarabina cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.