Infections

All Conditions

Symptoms and General Pathology

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Skin and Connective Tissue Diseases

Neoplasms

Recurrence

Communicable Diseases

Condylomata Acuminata

Virus Diseases

Papillomavirus Infections

Papilloma

Sexually Transmitted Diseases

Sexually Transmitted Diseases, Viral

DNA Virus Infections

Tumor Virus Infections

Genital Diseases

Urogenital Diseases

Disease Attributes

Antineoplastic Agents

All Drugs and Chemicals

Anti-Infective Agents

Imiquimod

Immunomodulating Agents

Immunologic Factors

Adjuvants, Immunologic

Interferons

Patients receive topical Imiquimod therapy for 12 weeks.

Imiquimod 5% cream

Patients receive topical Doritin therapy for 12 weeks

Placebo cream

Surgical Excision and Fulguration of condyloma

Fulguration

Irmgard E Kronberger, MD

Sascha Czipin, MD

Dietmar Öfner-Velano, MD

AdAM is a prospective, randomized, controlled, double-blinded, monocentric trial in patients receiving surgical therapy due to anal HPV infection.

Aim of the study is to evaluate efficacy of combination therapy (surgical therapy + topical Imiquimod-therapy). It is planned to include 200 patients.

100 patients receive surgical therapy+ topical Imiquimod therapy, 100 patients receive surgical therapy + topical Placebo therapy

Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial

Adjuvant Imiquimod Therapy to Reduce Recurrence Rate in Patients After Surgical Therapy of Anal HPV (Human Papilloma Virus)-Lesions

Recurrence is evaluated by clinical examination (proctoscopy)

Influence of CD4 cell count in the subgroup of HIV positive patients

Medical University Innsbruck

Leading Consultent

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

Central Nervous System Depressants

Anesthetics

After a recurrence in patient with previous low grade bladder cancer tumor, strict follow up with cystoscopy and cytology, avoiding immediate surgery

After a recurrence in patient with previous low grade bladder cancer tumor, fulguration under local anesthesia and sedation will be performed using a flexible cystoscope and a monopolar electrode

already included. WE will use Storz monopolar device for fulguration

Endoscopic fulguration

Fernando FL Lozano, MD

Biological behabiour of low grade bladder cancer tumors is well known. They have a very high rate of recurrences during their follow up but very low (less than 1%) risk of progression.

Until now, the gold standard of any bladder recurrence for this patients is performing an immediate transurethral ressection of the tumor.

This surgery has risk of complications and, due to the low risk of these subgroup of tumors, sometimes it becomes an overtreatment for the patients.

This is the reason why new conservative or less invasive surgeries are proposed to follow up and treat these patients.

Active Surveillance vs in Office Fulguration for Low Grade Bladder Cancer Tumors

Prospective Randomized Trial in Low Grade Bladder Tumors: Active Surveillance vs Endoscopic Fulguration.

codified information (anonymous information)

Number of patients that progress during the follow up

Number and grade of complications in both arms. Clavien Dindo Scale will be used

quality of life of the patients in both subgroups. CAVICAVENMI questionnaire will be used

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial	NCT03289260	Anogenital Huma... Condyloma Anal	Imiquimod 5% cr... Placebo cream Fulguration	18 Years -	Medical University Innsbruck
Active Surveillance vs in Office Fulguration for Low Grade Bladder Cancer Tumors	NCT05148728	Bladder Cancer	Endoscopic fulg...	18 Years -	Vall Hebron Insitut Recerca

Spots Global Cancer Trial Database for fulguration

Every month we try and update this database with for fulguration cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for fulguration

Every month we try and update this database with for fulguration cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for fulguration cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.