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Central Nervous System Diseases

Non-invasive brain intervention using MR-guided focused ultrasound

Non-invasive intervention with focused ultrasound (ExAblate 4000)

Javier - Fandino, MD

Ernst - Martin, MD

Focused Ultrasound Focused ultrasound is an attractive method for non-invasive thermal ablation of soft tissue tumors. Treatment begins by acquiring a series of MR images of the target organ. The physician then identifies a target volume in the MR images and delineates the treatment contours on the images. Therapy planning software calculates the parameters required to effectively treat the defined target volume. During the treatment an ultrasound transducer generates and focuses ultrasound energy to a focal point, called a sonication. The sonication raises the tissue temperature within a well-defined region to a degree, which causes thermal coagulation. MR images acquired during sonication provide a quantitative, real-time temperature map of the target area to confirm the location of the sonication and the size of the coagulated region. The sonication process is repeated at multiple adjacent points to cover the entire prescribed treatment volume.

Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors

MR-guided Ultrasound-Neurosurgery for the Treatment of Malignant Brain Tumors

Size of lesion in the tumor tissue for each sonication as a function of applied energy/temperature.

Number of Participants with Adverse Events as a Measure of Safety and Tolerability.

University Children's Hospital, Zurich

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors	NCT01698437	Malignant Brain...	Non-invasive in...	18 Years -	University Children's Hospital, Zurich
Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors	NCT01698437	Malignant Brain...	Non-invasive in...	18 Years -	University Children's Hospital, Zurich

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Every month we try and update this database with for fus cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for fus cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.