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Brief Title: Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors
Official Title: MR-guided Ultrasound-Neurosurgery for the Treatment of Malignant Brain Tumors
Study ID: NCT01698437
Brief Summary: Focused Ultrasound Focused ultrasound is an attractive method for non-invasive thermal ablation of soft tissue tumors. Treatment begins by acquiring a series of MR images of the target organ. The physician then identifies a target volume in the MR images and delineates the treatment contours on the images. Therapy planning software calculates the parameters required to effectively treat the defined target volume. During the treatment an ultrasound transducer generates and focuses ultrasound energy to a focal point, called a sonication. The sonication raises the tissue temperature within a well-defined region to a degree, which causes thermal coagulation. MR images acquired during sonication provide a quantitative, real-time temperature map of the target area to confirm the location of the sonication and the size of the coagulated region. The sonication process is repeated at multiple adjacent points to cover the entire prescribed treatment volume.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
MR-Center, University Children's Hospital, Zurich, , Switzerland
Name: Javier - Fandino, MD
Affiliation: Dept. of Neurosurgery, Kantonsspital Aarau, 5001 Aarau, Switzerland
Role: PRINCIPAL_INVESTIGATOR
Name: Ernst - Martin, MD
Affiliation: Center for MR-Research, University Children's Hospital Zurich, Switzerland
Role: PRINCIPAL_INVESTIGATOR