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Goiter, Nodular

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Bupivacaine

Anesthetics

Anesthetics, Local

After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.25% Marcaine.

After induction of general anesthesia the surgeon will perform local wound infiltration using 0.9% Saline.

After induction of general anesthesia the surgeon will perform a local wound infiltration using 0.25% Marcaine.

After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.9% saline.

0.25% Marcaine is injected lateral to the sternocleidomastoid bilaterally (10mL on each side) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

Superficial Cervical Plexus Block

0.50% Marcaine is injected at the site of incision (10mL) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

Local Wound Infiltration

0.9% saline

Marcaine

Raymon Grogan, MD

We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy. We hypothesize there is equivalent pain control between bilateral superficial cervical plexus block and local wound infiltration when used in conjunction with a general anesthetic.

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

A Randomized Control Trial Comparing Bilateral Superficial Cervical Plexus Block and Local Wound Infiltration in Thyroidectomy and Parathyroidectomy

The total amount of Fentanyl administered during the procedure will be recorded.

Pain scores will either be verbally reported to nursing and recorded or reported on a questionnaire. Back of neck pain scores range 0-10, throat pain scores range 0-9, incisional pain scores range 0-9 (zero means no pain and 9 or 10 means severe pain).

Nausea scores will either be verbally reported to nursing and recorded or reported on a questionnaire. The scores range 0-9 (zero means no symptom and 9 means "very severe").

Total operative opioid dosages administered converted to effective mg of Hydromorphine.

University of Chicago

After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.25% Marcaine.

Superficial Cervical Plexus Block: 0.25% Marcaine is injected lateral to the sternocleidomastoid bilaterally (10mL on each side) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

Marcaine

Superficial Cervical Block, Active

After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.9% saline.

Superficial Cervical Plexus Block: 0.25% Marcaine is injected lateral to the sternocleidomastoid bilaterally (10mL on each side) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

0.9% saline

Superficial Cervical Block, Placebo

After induction of general anesthesia the surgeon will perform a local wound infiltration using 0.25% Marcaine.

Local Wound Infiltration: 0.50% Marcaine is injected at the site of incision (10mL) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

Marcaine

Local Wound Infiltration, Active

After induction of general anesthesia the surgeon will perform local wound infiltration using 0.9% Saline.

Local Wound Infiltration: 0.50% Marcaine is injected at the site of incision (10mL) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.

0.9% saline

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy	NCT02205801	Thyroid Neoplas... Goiter, Nodular Thyroid Nodule Graves' Disease Hyperparathyroi...	Superficial Cer... Local Wound Inf... 0.9% saline Marcaine	18 Years -	University of Chicago
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy	NCT02205801	Thyroid Neoplas... Goiter, Nodular Thyroid Nodule Graves' Disease Hyperparathyroi...	Superficial Cer... Local Wound Inf... 0.9% saline Marcaine	18 Years -	University of Chicago
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy	NCT02205801	Thyroid Neoplas... Goiter, Nodular Thyroid Nodule Graves' Disease Hyperparathyroi...	Superficial Cer... Local Wound Inf... 0.9% saline Marcaine	18 Years -	University of Chicago

Spots Global Cancer Trial Database for goiter, nodular