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Liver Extracts

Entire fluorescence defect on the Lt. lobe of liver → Preservation of the aberrant left hepatic artery

Partial fluorecence defect on the Lt. lobe of liver → Ligation of the aberrant left hepatic artery

No fluorescence defect on the Lt. lobe of liver → Ligation of the aberrant left hepatic artery

Group1

Group2

Group3

" Hepatic artery variants are occasionally seen, especially 20-30% of aberrant left hepatic artery. In radical gastrectomy, decision for aberrant left hepatic artery(ALHA) ligation should consider the oncologic safety and liver-related complication. Theoretically, the ALHA preservation is the most ideal in the aspect of liver function protection. However, it is technically difficult which consumes much time. Not only that, oncologic safety could be threatened as some soft tissues, including lymph nodes, could be remained while in preserving the ALHA.

There has been no standardized method to evaluate the ALHA, and to decide whether preserve or ligate it.

This prospective study has been designed to develop the decision algorithm to define the ALHA preservation/ligation, using near-infrared fluorescence imaging during surgery. "

Enrolled patients will be divided into three groups according to the real time near-infrared fluorescence imaging during surgery.

Real-time Identification of the Aberrant Left Hepatic Arterial Territory in the Liver Using Near-infrared Fluorescence Imaging

Real-time Identification of the Aberrant Left Hepatic Arterial Territory in the Liver Using Near-infrared Fluorescence Imaging: Prospective Study to Develop Decision Algorithm to Define the Preservation/Ligation of an Aberrant Left Hepatic Artery

Investigator discretionally designed the decision algorithm for aberrant left hepatic artery preservation/ligation with real time near-infrared fluorescence imaging.

The order of the algorithm is as follows:

First, when surgeons identify the aberrant left hepatic artery during surgery, clamping the artery and injectioning indocyanine green (5mg/mL) intravenously would be performed.

After that, in a few seconds, liver perfusion could be detected through real time near-infrared fluorescence imaging.

The ligation or preservation of the aberrant left hepatic artery would be decided according to the proportion of the near-infrared fluorescence imaging defect. Investigator's like to confirm the safety and efficacity of this decision algorithm.

The elevated proprtion of the serum aspartate transaminase(AST, IU/L) and alanine transferase(ALT, IU/L) compared to preoperative value will be calculated and compared by groups.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Real-time Identification of the Aberrant Left Hepatic Arterial Territory in the Liver Using Near-infrared Fluorescence Imaging	NCT05971069	Stomach Neoplas...	Group1 Group2 Group3	20 Years - 80 Years	Gangnam Severance Hospital
Real-time Identification of the Aberrant Left Hepatic Arterial Territory in the Liver Using Near-infrared Fluorescence Imaging	NCT05971069	Stomach Neoplas...	Group1 Group2 Group3	20 Years - 80 Years	Gangnam Severance Hospital

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Spots Global Cancer Trial Database for group2

Every month we try and update this database with for group2 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for group2 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.