Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Antineoplastic Agents

All Drugs and Chemicals

Antirheumatic Agents

Paclitaxel

Cyclophosphamide

Albumin-Bound Paclitaxel

A a gentle, non-invasive form of energy-balancing work that promotes relaxation and can help manage the side effects of chemotherapy. It occurs every other week (during their infusion).

Guided relaxation every other week (during their infusion).

Healing Touch

Adriamycin, cyclophosphamide, and paclitaxel administered as standard of care

Standard care

guided relaxation

Kathy Turner, RN, NP

Alice "Ellie" Guardino, RN, NP

To study if Healing Touch is effective during chemotherapy treatment for breast cancer

To study the effectiveness of Healing Touch provided during chemotherapy infusions on the experience of women undergoing treatment for breast cancer. Healing Touch (HT) is a gentle, non-invasive form of energy-balancing work that promotes relaxation and can help manage the side effects of chemotherapy.

Healing Touch During Chemotherapy Infusions for Women With Breast Cancer

Stanford University

Behaviors and Mental Disorders

Anxiety Disorders

Panic Disorder

Heart rate variability (HRV) high frequency (HF) spectral analysis, before and after a 15 minute, one-time, guided relaxation program

Following 5 minute questionnaire, 15 minute rest and 5 minute heart rhythm recording, 15 minute relaxation program (listening via headphone to audio recording) to be completed by second heart rhythm recording and same questionnaire. Entire procedure 45-60 minutes.

Guided Relaxation

Ying Guo, MD

Primary:

* To characterize the physiologic changes of the autonomic nervous system, demonstrated by heart rate variability (HRV) high frequency (HF) spectral analysis, before and after a 15 minute, one-time, guided relaxation program for cancer patients.

Secondary:

* To assess whether change of HRV correlates with subjective feeling for anxiety, based on visual analog scale scores.

Rhythm changes in your heart rate are part of the "autonomic" nervous system. This is the part of your nervous system that controls the body functions that you do not have to think about. Researchers want to find out if a "guided relaxation" session will make your heart rate more variable, with more rhythm changes.

If you are found to be eligible to take part in this study, you will first answer a brief questionnaire that will measure several symptoms, such as pain and anxiety (worry). This questionnaire will take less than 5 minutes. You will also be asked questions about your alcohol and smoking history, and if you have ever used relaxation or meditation techniques in the past. This will also take less than 5 minutes.

You will then be asked to lay on your back, on a hospital bed or exam table. Electrodes will be placed along your chest, the same way they are placed for an electrocardiogram (ECG--a test to measure the electrical activity of the heart). You will be asked to rest for 15 minutes, and then your heart rhythm will be recorded for 5 minutes. After this first recording, you will begin the relaxation program by listening to an audio recording for about 15 minutes, using headphones. After the relaxation program has ended, your heart rhythm will be recorded for another 5-minute period while you are resting.

You will then be asked to complete the same questionnaire as before.

The entire procedure will take about 45-60 minutes. After this second questionnaire, your participation on this study will be over.

This is an investigational study. Up to 20 people will take part in this study. All will be enrolled at M. D. Anderson.

Relaxation and Heart Rate Variability

Pilot Study on the Effects of a Brief Relaxation Program on Heart Rate Variability in Cancer Patients

Total symptom burden as measured by Edmonton Symptom Assessment Scale (ESAS) in which there are eight visual analog scales (VAS) of 0 to 10, with 10 being most severe. The differences from ESAS baseline (before) to post (after) a 15 minute, one-time, guided relaxation program for each participant assessed, with the average difference in ESAS scores for all participants reported.

M.D. Anderson Cancer Center

Age Continuous

Sex: Female, Male

United States

Region of Enrollment

Ying Guo, MD, MS/Associate Professor

Heart rate variability (HRV) high frequency (HF) spectral analysis, before and after a 15 minute, one-time, guided relaxation program and summed ESAS scores

Analysis included all study participants.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Healing Touch During Chemotherapy Infusions for Women With Breast Cancer	NCT00533663	Breast Cancer	Healing Touch Standard care guided relaxati...	18 Years - 70 Years	Stanford University
Healing Touch During Chemotherapy Infusions for Women With Breast Cancer	NCT00533663	Breast Cancer	Healing Touch Standard care guided relaxati...	18 Years - 70 Years	Stanford University
Relaxation and Heart Rate Variability	NCT00735618	Cancer	Guided Relaxati...	-	M.D. Anderson Cancer Center

Spots Global Cancer Trial Database for guided relaxation