Symptoms and General Pathology

All Conditions

Nausea

Vomiting

Signs and Symptoms, Digestive

Anti-Dyskinesia Agents

Antiemetics

Central Nervous System Depressants

Psychotropic Drugs

Gastrointestinal Agents

All Drugs and Chemicals

Haloperidol

Haloperidol decanoate

Olanzapine

Antipsychotic Agents

Selective Serotonin Reuptake Inhibitors

Serotonin

Neurotransmitter Agents

Haldol

Jose Pereira

The purpose of this study is to compare the efficacy and safety of Haldol (haloperidol) and olanzapine in the control of chronic nausea with advanced cancer patients who have failed first line antiemetic therapy.

The purpose of this study is to compare the efficacy and safety of haloperidol and olanzapine in the control of chronic nausea with advanced cancer patients who have failed first line antiemetic therapy.

Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer

A Randomized Double-blind, Parallel Group Study Comparing Olanzapine (Zyprexa) With Haloperidol (Novo-peridol) for the Relief of Nausea and Vomiting in Patients With Advanced Cancer

Canadian Institutes of Health Research (CIHR)

Alberta Health services

Nervous System Diseases

Behaviors and Mental Disorders

Delirium

Confusion

Neurobehavioral Manifestations

Neurologic Manifestations

Neurocognitive Disorders

Mental Disorders

Psychotic Disorders

Cardiotonic Agents

Dopamine

Dopamine Antagonists

Dopamine Agents

Prior to stem cell transplant participants will receive 5mg of liquid or pill form, oral Haldol. Every other day visits will take place following the first administration of the study drug until 14 days after the transplant.

Michelle Weckmann, MD

This research study proposes to conduct an open label, feasibility study administering prophylactic oral haldol to patients undergoing a hematopoietic stem cell transplant (HSCT).

The study will address the following research aims: 1) To demonstrate the feasibility of enrolling HSCT patients in a prophylactic medication trial, 2) To determine the tolerability of oral haldol in HSCT patients and 2) To compare rates of delirium in HSCT patients who receive prophylactic haldol with an untreated historical control group.

This is an open label, safety \& feasibility, clinical drug trial. We will use historical controls from previous research with bone marrow transplant patients and delirium incidence at University of Iowa Hospitals and Clinics (UIHC) to evaluate the efficacy of prophylactic Haldol in the prevention of delirium. This study will recruit adult cancer patients undergoing hematopoietic stem cell transplant (HSCT) at UIHC.

Feasibility of Prophylactic Haldol to Prevent Delirium in Cancer Patients

Categorize and quantify adverse events from start of drug (day 1) to end of study drug per (CTCAE) version 4.0

American Cancer Society, Inc.

Michelle Weckmann

Clinical Assistant Professor

Prior to stem cell transplant participants will receive 5mg of liquid or pill form, oral Haldol. Every other day visits will take place following the first administration of the study drug until 14 days after the transplant.

Haldol

Oral Haldol in Patients Undergoing HSCT

Age, Categorical

Age, Continuous

Sex: Female, Male

United States

Region of Enrollment

Side Effects and Tolerability of Haldol in Patients With Undergoing Hematopoietic Stem Cell Transplant

Overall Study

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer	NCT00124930	Nausea Neoplasms	Olanzapine Haldol	18 Years -	AHS Cancer Control Alberta
Feasibility of Prophylactic Haldol to Prevent Delirium in Cancer Patients	NCT03489551	Stem Cell Trans... Delirium	Haldol	18 Years - 80 Years	University of Iowa

Spots Global Cancer Trial Database for haldol

Every month we try and update this database with for haldol cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for haldol

Every month we try and update this database with for haldol cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for haldol cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.