Neoplasms

Gland and Hormone Related Diseases

All Conditions

Thyroid Neoplasms

Thyroid Diseases

Thyroid Nodule

Endocrine System Diseases

Endocrine Gland Neoplasms

Head and Neck Neoplasms

Endoscopic procedure will be done by Harmonic ACE7+

Endoscopic procedure will be done by Ligasure

Ligasure™ Maryland Jaw Laparoscopic Sealer/Divider 37cm

Ligasure

Harmonic

Jin Wook Yi, Professor

Jin Wook Yi, Dr.

Open label randomized controlled study, for Harmonic versus Ligasure in transoral endoscopic thyroid surgery.

* This is a prospective randomized controlled study. The principal investigator or another clinical investigator in charge will individually inform the patients about the study, on the day before surgery.
* When informed consent is obtained, an investigator in charge of randomization only, will randomize the patients.
* According to randomization, the experimental group will Ligasure and the control group will use Harmonic ACE 7+. Other than the randomized use of energy devices, the protocol for TOETVA is performed as usual.
* Operation time (from insertion of the laparoscopic camera to removal of the camera), number of times the camera was cleaned, intraoperative blood loss will recorded.
* Postoperative hospital stay, visual analog pain scale, blood cell count and inflammatory parameters, postoperative drain amount will recorded.
* Complications of thyroid surgery (vocal cord dysfunction, hypoparathyroidism) are compared for safety assessment.

Energy Device Study in Transoral Endoscopic Thyroidectomy

Comparative Analysis Between Harmonic Versus LigaSure in Transoral Endoscopic Thyroidectomy: A Randomized Controlled Trial

Surgery time during the thyroid lobectomy

Numbers of camera cleaning during the lobectomy

Estimated blood loss during the lobectomy

visual analogue scale, ranged from 0-10 (0: no pain, 10: maximal pain)

Inha University Hospital

Assistant Professor

Skin and Connective Tissue Diseases

Breast Neoplasms

Breast Diseases

Skin Diseases

Dissection with harmonic scalpel in modified radical mastectomy

Dissection in modified radical mastectomy

electrocautery

Shaista M Khan, FRCS

To compare harmonic scalpel with electrocautery for outcomes i.e. estimated blood loss (EBL), operating time, drain Volume and drain Days, seroma formation, surgical site infection and postoperative pain in adult females undergoing MRM at a tertiary care hospital. We hypothesized that harmonic yields better outcome than electrocautery dissection.

In this randomized controlled trial, adult females who underwent MRM between April 2010 and July 2011 were randomized to receive either intervention A (harmonic scalpel) or B (electrocautery). The procedure was standardized except elevation of flaps and axillary dissection, that was performed as per randomization. Patients were followed up in clinic for four weeks. The outcomes were estimated blood loss (EBL), operating time, drain Volume and drain Days, complications (seroma, surgical site infection, hematoma and flap necrosis) and postoperative pain.

Use of Harmonic in Breast Surgery

Harmonic Scalpel vs. Electrocautery Dissection in Modified Radical Mastectomy: A Randomized Controlled Trial

Durations of drains in place after MRM: Patients were followed in clinic every 3rd day and drains were removed once the volume was \<30ml a day.

Time taken in minutes from incision to skin closure

Daily charting of drain volume at a specified time with regular recording in routine clinic follow ups till the drains were is place.

Patients were followed up till 3o days. If any of the following were found, the patient was labelled to have complication:

Seroma- fluctuant swelling under the flaps; SSI- as per CDC criteria; Hematoma- swelling under flaps with characteristic bruising; Flap necrosis- partial or complete necrosis of flaps.

Pain was measured by Visual Analogue score (1-10) by a registered nurse at 24 hours

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Energy Device Study in Transoral Endoscopic Thyroidectomy	NCT04320901	Thyroid Nodule Thyroid Cancer	Ligasure Harmonic	20 Years - 70 Years	Inha University Hospital
Energy Device Study in Transoral Endoscopic Thyroidectomy	NCT04320901	Thyroid Nodule Thyroid Cancer	Ligasure Harmonic	20 Years - 70 Years	Inha University Hospital
Use of Harmonic in Breast Surgery	NCT01587248	Breast Cancer Modified Radica...	Harmonic electrocautery	16 Years - 80 Years	Aga Khan University
Energy Device Study in Transoral Endoscopic Thyroidectomy	NCT04320901	Thyroid Nodule Thyroid Cancer	Ligasure Harmonic	20 Years - 70 Years	Inha University Hospital

Spots Global Cancer Trial Database for harmonic

Every month we try and update this database with for harmonic cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for harmonic

Every month we try and update this database with for harmonic cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for harmonic cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.