Neoplasms

Digestive System Diseases

All Conditions

Symptoms and General Pathology

Liver Neoplasms

Pain

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Liver Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Hematinics

Anesthetics

Liver Extracts

Group A: patients who received a HHB, TAPB, and LA

Group B: patients who received HHB and LA

Group C: patients who received TAPB and LA

Hepatic Hilar Block (HHB), Transversus Abdominis Plane Block (TAPB), and Local Anesthesia (LA)

HHB+TAPB+and LA

Hepatic Hilar Block (HHB) and Local Anesthesia (LA)

HHB+LA

Transversus Abdominis Plane Block (TAPB) and Local Anesthesia (LA)

TAPB+LA

Lu Wang

Man Lu, PHD

Patients with liver tumors who underwent US-guided-MWA of liver tumors were enrolled. These patients were allocated into three groups based on tumor size and number: A, B, and C. Prior to the ablation procedure, Group A patients received a combination of hepatic hilar block (HHB), Transversus abdominis plane block (TAPB), and local anesthesia (LA). Patients in Group B were administered HHB in conjunction with LA, while those in Group C received TAPB and LA. Evaluative parameters included the Numerical Rating Scale (NRS) scores, consumption of morphine, incidence of complications, and factors influencing perioperative pain.

Patients with liver tumors who underwent US-guided-MWA of liver tumors were enrolled. These patients were allocated into three groups based on tumor size and number: A, B, and C. Prior to the ablation procedure, Group A patients received a combination of hepatic hilar block (HHB), Transversus abdominis plane block (TAPB), and local anesthesia (LA). Patients in Group B were administered HHB in conjunction with LA, while those in Group C received TAPB and LA.Pain levels were routinely assessed through the Numerical Rating Scale (NRS), with scores being recorded by the attending nurse every 15 minutes. The frequency of these assessments would be increased if the patient reported discomfort or if there were changes observed in vital signs. If a patient reported a pain level of ≥4 on the NRS scale, an intravenous dose of 10mg morphine was administered, provided that cardiopulmonary safety could be assured. The determination of cardiopulmonary safety was made by the interventional radiologist (M. L. with 20 years of experience). Following the ablation procedure, all patients were monitored for a period of 36 hours. During this period, several parameters were recorded at the time of the procedure and again at 4, 8-, 12-, 24-, and 36-hours post-procedure. These parameters included the NRS score, vital signs, any need for morphine, and the occurrence of any adverse events.

CMRA for US-guided-MWA of Liver Tumors

Combined Multiple Regional Anesthesia for Microwave Ablation of Liver Tumors

NRS score was used to evaluate pain control

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
CMRA for US-guided-MWA of Liver Tumors	NCT05990257	Regional Anesth... Pain Control Microwave Ablat... Liver Tumors	HHB+TAPB+and LA HHB+LA TAPB+LA	18 Years - 80 Years	Sichuan Cancer Hospital and Research Institute
CMRA for US-guided-MWA of Liver Tumors	NCT05990257	Regional Anesth... Pain Control Microwave Ablat... Liver Tumors	HHB+TAPB+and LA HHB+LA TAPB+LA	18 Years - 80 Years	Sichuan Cancer Hospital and Research Institute

Spots Global Cancer Trial Database for hhb+tapb+and la