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Spots Global Cancer Trial Database for hr+

Every month we try and update this database with for hr+ cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBCNCT05191004
Advanced Breast...
Metastatic Brea...
Breast Cancer
Breast Carcinom...
Cancer of the B...
Cancer of Breas...
Malignant Tumor...
Breast Tumor
NUV-422
Fulvestrant
18 Years - Nuvation Bio Inc.
Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast CancerNCT02947685
HER-2 Positive ...
Estrogen Recept...
palbociclib
trastuzumab
pertuzumab
letrozole
Anastrozole
Exemestane
Fulvestrant
18 Years - Alliance Foundation Trials, LLC.
Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant in Japanese Men and Postmenopausal Women With Advanced Breast CancerNCT04524000
Advanced Breast...
Alpelisib
Fulvestrant
18 Years - Novartis
A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORiNCT01633060
Metastatic Brea...
Fulvestrant
BKM120
BKM120 matching...
18 Years - Novartis
Aromatase Inhibitor and Durvalumab in Postmenopausal Breast CancerNCT03874325
Breast Cancer
Hormone Recepto...
Durvalumab
Anastrozole 1mg
Letrozole 2.5mg
Exemestane 25 M...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line TreatmentNCT06311383
Breast Cancer
First-line Ribo...
First-line endo...
First-line chem...
18 Years - Novartis
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.NCT02437318
Breast Cancer
Fulvestrant
Alpelisib
Alpelisib place...
18 Years - Novartis
Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast CancerNCT05064085
Hormone Recepto...
Cemiplimab
Capecitabine
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Study in Women With Advanced Breast Cancer Receiving Palbociclib With AI or FulvestrantNCT02894398
Breast Cancer
Hormone Recepto...
Human Epidermal...
Palbociclib
Letrozole
Anastrozole
Exemestane
Fulvestrant
18 Years - iOMEDICO AG
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA StudyNCT05645536
Breast Cancer
TOL2506
Tamoxifen
Letrozole table...
Anastrozole Tab...
Exemestane Tabl...
18 Years - 51 YearsTolmar Inc.
Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.NCT02437318
Breast Cancer
Fulvestrant
Alpelisib
Alpelisib place...
18 Years - Novartis
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBCNCT05191004
Advanced Breast...
Metastatic Brea...
Breast Cancer
Breast Carcinom...
Cancer of the B...
Cancer of Breas...
Malignant Tumor...
Breast Tumor
NUV-422
Fulvestrant
18 Years - Nuvation Bio Inc.
Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and FulvestrantNCT04899349
Breast Cancer
Alpelisib
Fulvestrant
Metformin XR
Dapagliflozin +...
Dapagliflozin
18 Years - Novartis
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast CancerNCT04906395
Breast Cancer
TOL2506
Tamoxifen
Letrozole Table...
Anastrozole Tab...
Exemestane Tabl...
18 Years - 49 YearsTolmar Inc.
Efficacy and Safety of Ribociclib in Pre- and Postmenopausal Chinese Women With HR Positive, HER2-negative, Advanced Breast Cancer.NCT03671330
Breast Cancer
Ribociclib Plac...
Ribociclib
NSAI: Letrozole...
Letrozole
Goserelin
18 Years - 60 YearsNovartis
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA StudyNCT05645536
Breast Cancer
TOL2506
Tamoxifen
Letrozole table...
Anastrozole Tab...
Exemestane Tabl...
18 Years - 51 YearsTolmar Inc.
Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast CancerNCT05064085
Hormone Recepto...
Cemiplimab
Capecitabine
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast CancerNCT04906395
Breast Cancer
TOL2506
Tamoxifen
Letrozole Table...
Anastrozole Tab...
Exemestane Tabl...
18 Years - 49 YearsTolmar Inc.
Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and FulvestrantNCT04899349
Breast Cancer
Alpelisib
Fulvestrant
Metformin XR
Dapagliflozin +...
Dapagliflozin
18 Years - Novartis
A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to SurgeryNCT05549505
Breast Cancer
ARV-471
Anastrozole
Surgical resect...
18 Years - Arvinas Inc.
Aromatase Inhibitor and Durvalumab in Postmenopausal Breast CancerNCT03874325
Breast Cancer
Hormone Recepto...
Durvalumab
Anastrozole 1mg
Letrozole 2.5mg
Exemestane 25 M...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast CancerNCT03219476
Breast Cancer
Invasive Breast...
Anastrozole
Letrozole
Exemestane
Tamoxifen
18 Years - Medical College of Wisconsin
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