Spots Global Cancer Trial Database for invasive breast cancer
Every month we try and update this database with for invasive breast cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Sentinel Lymph Node Biopsy in Clinically Node-negative Early Breast Cancer Patients After Neoadjuvant Chemotherapy | NCT03381092 | Invasive Breast... | - 70 Years | Peking University | ||
| Examining Bioactivity of PVSRIPO in Invasive Breast Cancer | NCT03564782 | Invasive Breast... | PVSRIPO | 18 Years - | Istari Oncology, Inc. | |
| Therapy for Locally Advanced Breast Cancer Using Doxil, Paclitaxel, and Cyclophosphamide With Avastin | NCT00635050 | Invasive Breast... | Doxil, Paclitax... | 19 Years - | University of Alabama at Birmingham | |
| Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma | NCT06357338 | Invasive Breast... | no intervention | 15 Years - | Sohag University | |
| Therapy for Locally Advanced Breast Cancer Using Doxil, Paclitaxel, and Cyclophosphamide With Avastin | NCT00635050 | Invasive Breast... | Doxil, Paclitax... | 19 Years - | University of Alabama at Birmingham | |
| Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer. | NCT05318274 | Ductal Breast C... Invasive Breast... Early-stage Bre... Stage 0 Breast ... Stage I Breast ... Stage IA Breast... Stage IB Breast... | Hypofractionate... | 18 Years - | Coordinación de Investigación en Salud, Mexico | |
| ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases | NCT00496379 | Breast Cancer CNS Disease | ZK219477 | 18 Years - | Dana-Farber Cancer Institute | |
| TRUDI: TDXD+Durva in HER2+/Low IBC | NCT05795101 | Invasive Breast... Inflammatory Br... HER2-positive B... HER2 Low Breast... Breast Cancer | Trastuzumab der... Durvalumab | 18 Years - | Dana-Farber Cancer Institute | |
| Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients | NCT04262518 | Breast Cancer Invasive Breast... Metastatic Brea... Breast Carcinom... Metastatic Brea... | Outcomes4Me Mob... | 18 Years - | Outcomes4Me | |
| Sentinel Lymph Node Biopsy in Clinically Node-negative Early Breast Cancer Patients After Neoadjuvant Chemotherapy | NCT03381092 | Invasive Breast... | - 70 Years | Peking University | ||
| HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer Post Neoadjuvant Chemotherapy | NCT02061423 | Breast Cancer | HER-2 pulsed De... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| The Prone Breast Radiation Therapy Trial | NCT01815476 | Ductal Carcinom... Invasive Breast... | Radiation Thera... | - | Toronto Sunnybrook Regional Cancer Centre | |
| Alpha Radiation Emitters Device for the Treatment of Newly Diagnosed Breast Carcinoma Patients With Distant Metastases | NCT03970967 | Breast Carcinom... Metastatic Brea... Invasive Breast... Distant Metasta... | Device: Radiati... | 45 Years - | Alpha Tau Medical LTD. | |
| EpCAM and p53 Expressions in Infiltrating Duct Carcinoma of the Breast | NCT05703815 | Invasive Breast... | 20 Years - 80 Years | Sohag University | ||
| A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer | NCT05412225 | Breast Cancer Invasive Breast... | Pre-neoadjuvant... Neoadjuvant rad... Unilateral tota... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| MRI Radiomics Assessing Neoadjuvant Chemotherapy in Breast Cancer to Predict Lymph Node Metastasis and Prognosis(RBC-02) | NCT04004559 | Invasive Breast... Neoadjuvant Che... Radiomics Axillary Lymph ... Prognosis | No intervention... | 18 Years - 75 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab | NCT00625898 | Breast Cancer | Docetaxel Trastuzumab Carboplatin Bevacizumab 5-Fluorouracil Epirubicin Cyclophosphamid... | 18 Years - | NSABP Foundation Inc | |
| Contribution of 18FDG PET-Scan in Tumour Volume Determination in Patients Operated of Breast Cancer | NCT01621529 | Infiltrating Du... | 18 Years - | Centre Henri Becquerel | ||
| Suction Drain Versus the Use of Adaptive Skin Sutures After Mastectomy ± Axillary Lymphadenectomy; a Prospective Randomised Study | NCT01509781 | in Situ Breast ... Invasive Breast... | Insertion of su... Adaptive skin s... | - 75 Years | National Institute of Oncology, Hungary | |
| Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma | NCT06357338 | Invasive Breast... | no intervention | 15 Years - | Sohag University | |
| Axillary Node Dissection Versus no Dissection in Breast Cancer With Positive Sentinel Lymph Node | NCT01717131 | Invasive Breast... | Surgery for sta... No axillary lym... | 18 Years - | Institut Paoli-Calmettes | |
| AKT Inhibitor in Oestrogen Positive Breast Cancer | NCT02077569 | Invasive Breast... | AZD5363 | 18 Years - | University of Nottingham | |
| Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy | NCT06268665 | Breast Cancer Breast Cancer S... Breast Cancer S... Breast Cancer S... Breast Cancer S... Invasive Breast... Ovarian Cancer Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Ovarian Cancer ... Breast Cancer S... Breast Cancer I... Breast Cancer, ... Breast Cancer, ... Breast Cancer S... Breast Cancer S... Breast Cancer S... Breast Cancer S... Cancer, Breast Tumors, Breast Mammary Cancer Mammary Carcino... Breast Carcinom... Breast Neoplasm Malignant Breas... Malignant Tumor... Cancer of Ovary Ovary Cancer Ovary Neoplasm | Tart Cherry Jui... | 18 Years - | University of California, Davis | |
| AKT Inhibitor in Oestrogen Positive Breast Cancer | NCT02077569 | Invasive Breast... | AZD5363 | 18 Years - | University of Nottingham | |
| Development of Multi-specific Antibodies Based on Immune Microenvironment of Breast Cancer | NCT05767931 | Invasive Breast... | 18 Years - 70 Years | Peking University | ||
| Suction Drain Versus the Use of Adaptive Skin Sutures After Mastectomy ± Axillary Lymphadenectomy; a Prospective Randomised Study | NCT01509781 | in Situ Breast ... Invasive Breast... | Insertion of su... Adaptive skin s... | - 75 Years | National Institute of Oncology, Hungary | |
| Sentinel Lymph Node After Neoadjuvant Chemotherapy in Breast Carcinoma | NCT03630913 | Invasive Breast... Axillary Metast... | Tagged axillary... | 18 Years - | Institut Cancerologie de l'Ouest | |
| Re-Evaluation of Tumor Samples From Women With Breast Cancer With the in Vitro Diagnostic Kit "MammaTyperTM" | NCT02244580 | Invasive Breast... | MammaTyper™ | 18 Years - 65 Years | BioNTech Diagnostics GmbH | |
| Capecitabine in Women With Operable Breast Cancer | NCT00148720 | Invasive Breast... Primary Invasiv... Stage I Breast ... Stage II Breast... Stage III Breas... | Capecitabine | 18 Years - | Dana-Farber Cancer Institute | |
| Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging | NCT01060085 | Ductal Carcinom... Invasive Breast... | 30 Years - | Dartmouth-Hitchcock Medical Center | ||
| Prediction of Upgrade to Invasive Cancer in Patients Diagnosed With Ductal Carcinoma in Situ by Percutaneous Core Needle Biopsy | NCT04498611 | Carcinoma, Duct... Invasive Breast... IMAGE | contrast-enhanc... | 19 Years - | Seoul National University Hospital | |
| Axillary Reverse Mapping (ARM) Technique | NCT03109522 | Invasive Breast... Ductal Carcinom... | axillary revers... Standard axilla... | 18 Years - | McMaster University | |
| Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Early Breast Cancer | NCT00983684 | Invasive Breast... Breast Cancer | Intrabeam Post-operative ... | 45 Years - | University College, London | |
| Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients | NCT04262518 | Breast Cancer Invasive Breast... Metastatic Brea... Breast Carcinom... Metastatic Brea... | Outcomes4Me Mob... | 18 Years - | Outcomes4Me | |
| Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer | NCT04553770 | Early-stage Bre... Hormone Recepto... Invasive Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas... Stage III Breas... | Anastrozole Therapeutic Con... Trastuzumab Der... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE) | NCT06085274 | Breast Cancer | ICG guided sent... | 18 Years - 80 Years | University Health Network, Toronto | |
| Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor | NCT01765049 | Invasive Breast... Estrogen Recept... | - 70 Years | Seoul National University Hospital | ||
| ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases | NCT00496379 | Breast Cancer CNS Disease | ZK219477 | 18 Years - | Dana-Farber Cancer Institute | |
| The Use of Deep Inspiration Breath Hold and Prone Irradiation to Decrease Cardiac Radiation Exposure | NCT03375892 | Breast Cancer Ductal Carcinom... Invasive Breast... | Deep Inspiratio... Free breathing ... | 18 Years - | Medical College of Wisconsin | |
| BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT) | NCT04296942 | Breast Cancer Triple Negative... HER2+ Breast Ca... Hormone Recepto... Metastatic Brea... | Brachyury-TRICO... Entinostat M7824 Ado-trastuzumab... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Pegylated Liposomal Doxorubicin or Epirubicin in Neoadjuvant or Adjuvant Chemotherapy for Breast Cancer. | NCT03983096 | Breast Cancer | 18 Years - 70 Years | Tianjin Medical University Cancer Institute and Hospital | ||
| Effect of Ultrasound Combined With Microbubbles on Blood Perfusion in Invasive Breast Cancer | NCT06158217 | Invasive Breast... Cavitation Perfusion | ultrasound comb... | 18 Years - | Beijing Friendship Hospital | |
| RNA Disruption Assay (RDA) Response Prediction in Neoadjuvant Chemotherapy Breast Cancer Treatment | NCT02190227 | Invasive Breast... | Tumor RDA biops... | 18 Years - | Jewish General Hospital | |
| Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer | NCT06281145 | Breast Cancer Colon Cancer | Heart-rate vari... | 18 Years - | Comenius University | |
| Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers | NCT00225927 | Breast Cancer I... Stage 0 Breast ... | radioguided see... | 18 Years - | McMaster University | |
| Genetic Testing for All Breast Cancer Patients (GET FACTS) | NCT04245176 | Breast Cancer Invasive Breast... in Situ Breast ... Genetic Testing | Standard Geneti... Quantitative Ge... | 18 Years - 79 Years | Dana-Farber Cancer Institute | |
| Fulvestrant + Neratinib In Breast Cancer | NCT04901299 | Stage IV (Metas... Metastatic Brea... ER Positive Bre... PR-Positive Bre... HER2-negative B... Invasive Breast... | NERATINIB FULVESTRANT | 18 Years - | Massachusetts General Hospital | |
| Radiation Therapy Followed by Surgery in Treating Patients With Early-Stage Breast Cancer | NCT01024582 | Breast Cancer | biopsy fine-needle asp... accelerated par... image-guided ra... | 60 Years - 120 Years | The Netherlands Cancer Institute | |
| Lapatinib +/- Trastuzumab In Addition To Standard Neoadjuvant Breast Cancer Therapy. | NCT00524303 | Neoplasms, Brea... | Trastuzumab Paclitaxel FEC75 Lapatinib | 18 Years - | GlaxoSmithKline | |
| A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer | NCT05412225 | Breast Cancer Invasive Breast... | Pre-neoadjuvant... Neoadjuvant rad... Unilateral tota... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Breast Density Change Predicting Response to Adjuvant Aromatase Inhibitor | NCT01765049 | Invasive Breast... Estrogen Recept... | - 70 Years | Seoul National University Hospital | ||
| Anti-Hormone Therapy (With Anastrazole and Fulvestrant) Before Surgery to Treat Postmenopausal Women With Breast Cancer. | NCT00921115 | Invasive Breast... | Fulvestrant Anastrazole | 18 Years - | University of Kansas Medical Center | |
| Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer. | NCT05318274 | Ductal Breast C... Invasive Breast... Early-stage Bre... Stage 0 Breast ... Stage I Breast ... Stage IA Breast... Stage IB Breast... | Hypofractionate... | 18 Years - | Coordinación de Investigación en Salud, Mexico | |
| Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer | NCT04648904 | Invasive Breast... Post-mastectomy | Radiotherapy | 30 Years - | Memorial Sloan Kettering Cancer Center | |
| Fulvestrant in Premenopausal Women With Hormone Receptor-Positive Breast Cancer | NCT00146601 | Breast Cancer | Fulvestrant | 18 Years - | Dana-Farber Cancer Institute | |
| Suction Drain Versus the Use of Adaptive Skin Sutures After Mastectomy ± Axillary Lymphadenectomy; a Prospective Randomised Study | NCT01509781 | in Situ Breast ... Invasive Breast... | Insertion of su... Adaptive skin s... | - 75 Years | National Institute of Oncology, Hungary | |
| Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy | NCT03566394 | Invasive Breast... Chemotherapeuti... Myalgia Arthralgia | Gabapentin 300m... | 18 Years - | British Columbia Cancer Agency | |
| Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity | NCT04245150 | DCIS Invasive Breast... | Stool sample Skin Swab Sampl... | 18 Years - | Case Comprehensive Cancer Center | |
| fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases | NCT06328465 | Invasive Breast... HER2-positive B... Triple Negative... | Diffusion whole... | 18 Years - 75 Years | European Institute of Oncology | |
| Mometasone Furoate 0.1% Versus Eucerin on Moderate to Severe Skin Toxicities in Breast Cancer Patients Receiving Postmastectomy Radiation | NCT01856543 | Invasive Breast... | Eucerin Mometasone Furo... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer | NCT04553770 | Early-stage Bre... Hormone Recepto... Invasive Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas... Stage III Breas... | Anastrozole Therapeutic Con... Trastuzumab Der... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Lapatinib +/- Trastuzumab In Addition To Standard Neoadjuvant Breast Cancer Therapy. | NCT00524303 | Neoplasms, Brea... | Trastuzumab Paclitaxel FEC75 Lapatinib | 18 Years - | GlaxoSmithKline | |
| Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer | NCT06281145 | Breast Cancer Colon Cancer | Heart-rate vari... | 18 Years - | Comenius University | |
| Safety and Efficacy of Omission of Sentinel Node Biopsy in Patients With Estrogen-Positive Breast Cancer Over Age 65 | NCT02564848 | Breast Cancer | Lumpectomy with... | 65 Years - | Cedars-Sinai Medical Center | |
| Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer | NCT03206203 | Triple Negative... Stage IV Breast... HER2 Negative Invasive Breast... | Atezolizumab Carboplatin Laboratory Biom... Quality-of-Life... | 18 Years - | Vanderbilt-Ingram Cancer Center | |
| Prospective Breast Cancer Biospecimen Collection | NCT04074720 | Breast Cancer Invasive Breast... Carcinoma in Si... | Tissue Sample c... Blood Sample Co... Rectal Swab | 18 Years - | Thomas Jefferson University | |
| Preoperative Testing of the Anti-Progesterone Mifepristone in Early Stage Breast Cancer | NCT01138553 | Invasive Breast... Ductal Carcinom... | Mifepristone | 18 Years - | University of California, San Diego | |
| CONFIRM: Magnetic Resonance Guided Radiation Therapy | NCT04368702 | Gastric Cancer Invasive Breast... in Situ Breast ... Mantle Cell Lym... Larynx Cancer Bladder Cancer | Viewray MRIdian... | 18 Years - | Dana-Farber Cancer Institute | |
| Safety and Efficacy of Omission of Sentinel Node Biopsy in Patients With Estrogen-Positive Breast Cancer Over Age 65 | NCT02564848 | Breast Cancer | Lumpectomy with... | 65 Years - | Cedars-Sinai Medical Center | |
| Overall Diet Quality and Breast Cancer Risk | NCT03304171 | Invasive Breast... Incident Breast... | - | University of California, Irvine | ||
| Evaluate Trastuzumab Plus Standard Chemotherapy Given Before Surgery in Breast Cancer Patients With Low HER 2 Expression | NCT00944047 | Breast Cancer | nab-paclitaxel trastuzumab Doxorubicin cyclophosphamid... Growth Factor S... Surgery | 18 Years - | University of Kansas Medical Center | |
| Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma | NCT06357338 | Invasive Breast... | no intervention | 15 Years - | Sohag University | |
| Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer | NCT04553770 | Early-stage Bre... Hormone Recepto... Invasive Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas... Stage III Breas... | Anastrozole Therapeutic Con... Trastuzumab Der... | 18 Years - | Jonsson Comprehensive Cancer Center | |
| Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer | NCT04648904 | Invasive Breast... Post-mastectomy | Radiotherapy | 30 Years - | Memorial Sloan Kettering Cancer Center | |
| Axillary Lymph Node Status After Completion of Preoperative Neoadjuvant Systemic Chemotherapy in Patients | NCT00507611 | Invasive Breast... | Sentinel node m... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Re-Evaluation of Tumor Samples From Women With Breast Cancer With the in Vitro Diagnostic Kit "MammaTyperTM" | NCT02244580 | Invasive Breast... | MammaTyper™ | 18 Years - 65 Years | BioNTech Diagnostics GmbH | |
| Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC | NCT03361800 | Breast Cancer Invasive Breast... ER-Negative PR-... | Entinostat | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Selective Image Guided Resection of Axillary Lymph Nodes | NCT01880645 | Breast Cancer | Fine Needle Asp... Ultrasound Breast Surgery ... | 18 Years - | M.D. Anderson Cancer Center | |
| Pre-Surgical Intervention for Targeted Therapies for Breast Cancer | NCT01004744 | Invasive Breast... | Anastrozole | 21 Years - | Columbia University | |
| Alpha Radiation Emitters Device for the Treatment of Newly Diagnosed Breast Carcinoma Patients With Distant Metastases | NCT03970967 | Breast Carcinom... Metastatic Brea... Invasive Breast... Distant Metasta... | Device: Radiati... | 45 Years - | Alpha Tau Medical LTD. |
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