Neoplasms

All Conditions

Respiratory Tract (Lung and Bronchial) Diseases

Rare Diseases

Carcinoma

Small Cell Lung Carcinoma

Carcinoma, Small Cell

Lung Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Small Cell Lung Cancer

hypofractionated concurrent chemoradiotherapy

conventionally fractionated concurrent chemoradiotherapy

For patients with Limited Disease Small Cell Lung Cancer, 45Gy/15F of radiotherapy with concurrent chemotherapy will be used in experimental arm.

For patients with Limited Disease Small Cell Lung Cancer, 60Gy/30F of radiotherapy with concurrent chemotherapy will be used in the control arm.

LuHua Wang, MD

LUHUA WANG, MD

Luhua Wang, MD

The purpose of this study is to determine whether hypofractionated concurrent chemo-radiotherapy has the same efficiency as conventionally fractionated concurrent chemo-radiotherapy in Limited Disease Small Cell Lung Cancer.

For patients with Limited Disease Small Cell Lung Cancer, 45Gy/15F of radiotherapy with concurrent chemotherapy will be used in experimental arm. While 60Gy/30F of radiotherapy with concurrent chemotherapy will be used in the control arm. Both survival and toxicity of the two arms will be observed and compared.

Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC

Phase III Randomized Study of Hypofractionated vs Conventionally Fractionated Concurrent Chemo-radiotherapy for Limited Disease Small Cell Lung Cancer

Incidence of tumor recurrence in local or regional area

Incidence of radiotherapy and chemotherapy induced toxicities assessed by CTCAE v 4.0

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC	NCT02688036	Carcinoma, Smal... Lung Neoplasms	hypofractionate... conventionally ...	18 Years - 70 Years	ChineseAMS
Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC	NCT02688036	Carcinoma, Smal... Lung Neoplasms	hypofractionate... conventionally ...	18 Years - 70 Years	ChineseAMS

Spots Global Cancer Trial Database for hypofractionated concurrent chemoradiotherapy