Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Rare Diseases

Melanoma

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Neoplasms

Skin Diseases

Neuroendocrine Tumor

Neuroepithelioma

Subjects with Choroidal Melanoma or Indeterminate Lesions.

Medical Monitor

Amy Merz

Rosaleen Ostrick

Mariana Nunez

Grayson Hanlon

Pamela Campbell

Kendra Mellert

Andi Gilchrist, BS CMSS

Ellen Alt

Ann Lundquist

Lisa Flynn

Lauren Frazier

Lisa Walden

Sally Arceneaux

Allison Stroh

Bonnie Verges

The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse events, information about pregnancy and symptomatic overdose.

This is a multi-center long-term observational Registry of subjects with Primary Indeterminate Lesions or Choroidal Melanoma.

The Registry will initially be open to subjects who have previously participated in an Aura Biosciences bel-sar sponsored clinical trial for their primary Choroidal Melanoma or Indeterminate Lesions.

All subjects will be followed for a minimum of 5 years (including time enrolled in an Aura sponsored clinical trial), until withdrawal of consent, or until death whichever comes first.

No interventions will be required as part of the Registry. Data collection will be based on IL or CM information anticipated to be available based on the standard of care for subjects with CM or IL.

A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma

Aura Biosciences

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma	NCT03941379	Choroidal Melan... Indeterminate L...		18 Years -	Aura Biosciences
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma	NCT03941379	Choroidal Melan... Indeterminate L...		18 Years -	Aura Biosciences

Spots Global Cancer Trial Database for indeterminate lesions of eye