Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Nervous System Diseases

Symptoms and General Pathology

Nutritional and Metabolic Diseases

Carcinoma, Non-Small-Cell Lung

Sarcopenia

Lung Neoplasms

Malnutrition

Carcinoma

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Carcinoma, Bronchogenic

Bronchial Neoplasms

Nutrition Disorders

Muscular Atrophy

Atrophy

Neuromuscular Manifestations

Neurologic Manifestations

Pathological Conditions, Anatomical

Patients diagnosed with NSCLC meeting Stage IA-IIIA as well as sarcopenia by the enrollment

Patients diagnosed with NSCLC meeting Stage IA-IIIA but without sarcopenia by the enrollment

Bioelectrical Impedance Analysis with Inbody 570 (Inbody Co., Seoul, Korea) during each follow-up

Inbody 570

Handgrip strength measurement using a JAMAR Dynamometer (JAMAR Co., Ltd., USA) during each follow-up

JAMAR Dynamometer

Chest and abdominal CT scan during each follow-up

CT scan

Ting Zhao, MD

Ying-gang Zhu, MD, PhD

Growing evidence has confirmed that the prognosis of lung cancer is not only related to the stage of disease, but also to the physiological and psychological situation of the patients. Malignant tumors are often associated with weakness and cachexia, leading to less physical activities and worse moods. However, few studies that have attempted to investigate the impact of nutritional status on the prognosis of NSCLC. Existing applications of nutritional scoring systems in early-stage of NSCLC are very limited. Therefore, this study aims to observe the correlation between nutritional status and the prognosis of patients with early-stage NSCLC, to clarify the value in predicting the overall survival rate and progression-free survival rate of NSCLC patients, and to offer evidence for alleviating the social and economic burden of NSCLC.

The prognosis of lung cancer is not only related to the stage of disease, but also to the physiological and psychological situation of the patients. Malignant tumors are often associated with weakness and cachexia, leading to less physical activities and worse moods. However, few studies that have attempted to investigate the impact of nutritional status on the prognosis of NSCLC. Existing applications of nutritional scoring systems in early-stage of NSCLC are very limited. Therefore, this study aims to observe the correlation between nutritional status and the prognosis of patients with early-stage NSCLC, to clarify the value in predicting the overall survival rate and progression-free survival rate of NSCLC patients, and to offer evidence for alleviating the social and economic burden of NSCLC.

Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer

Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer (Stage IA to IIIA)

Time from diagnosis to clinically recorded disease progression or death from any cause

Outcome of patient death from diagnosis to any cause or the final follow-up time

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer	NCT05212285	Sarcopenia Non Small Cell ... Malnutrition	Inbody 570 JAMAR Dynamomet... CT scan	18 Years - 85 Years	Fudan University
Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer	NCT05212285	Sarcopenia Non Small Cell ... Malnutrition	Inbody 570 JAMAR Dynamomet... CT scan	18 Years - 85 Years	Fudan University

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