Neoplasms

Digestive System Diseases

All Conditions

Rare Diseases

Esophageal Neoplasms

Carcinoma

Carcinoma, Squamous Cell

Esophageal Cancer

KK2260 will be administered intravenously at several dose levels, and after determining MTD, multiple dose regimens will be evaluated in multiple cancer types to target.

KK2260

Kyowa Kirin Co., Ltd.

This is the first in human study of KK2260. In Part 1, the maximum tolerated dose (MTD) will be determined while evaluating the safety and tolerability of KK2260 in patients with advanced or metastatic solid tumors (any cancer type). Part 2 will compare the safety and tolerability of KK2260 in patients with multiple cancer types in multiple dose regimen arms.

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

A Phase 1, Uncontrolled, Open-label, Non-randomized, Dose-escalation Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors, Followed by an Uncontrolled, Randomized Study in Patients With Esophageal Cancer or Head and Neck Squamous Cell Carcinoma

The datasets generated and/or analyzed during the study sponsored by Kyowa Kirin will be available in the Vivli repository, https://vivli.org/ourmember/kyowa-kirin/ as long as conditions of data disclosure specified in the policy section of the Vivli website are satisfied.

Prothrombin time international normalized ratio and Activated partial thromboplastin time

The resting Heart rate, PR interval, QRS interval, QT interval, and QTc intervals will be recorded. Any abnormalities in ECG will be specified and documented as clinically significant or not clinically significant.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors	NCT06248411	Advanced or Met...	KK2260 KK2260	18 Years -	Kyowa Kirin Co., Ltd.
A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors	NCT06248411	Advanced or Met...	KK2260 KK2260	18 Years -	Kyowa Kirin Co., Ltd.

Spots Global Cancer Trial Database for kk2260

Every month we try and update this database with for kk2260 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for kk2260

Every month we try and update this database with for kk2260 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for kk2260 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.