Neoplasms

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Bone Diseases

Patients with MUTARS® modular reconstruction prostheses following primary or secondary knee bone malignancy with minimal follow-up of one year

MUTARS® modular reconstruction prostheses

Christophe Szymanski, MD

The placement of mega knee prosthesis is a necessity after a large tumor resection and oncological. These mega knee prostheses implanted in the context of oncological surgery have been very few evaluated in the literature.

Active knee extension is essential in order to walk properly. The study propose the evaluation of this prosthesis by checking the possibility of locking of the prosthetic joint and thus the possibility of active walking.

A more in-depth, isokinetic analysis at 1 year of follow-up will also be done in an exploratory manner, as the literature has no data on this subject.

Functional Outcomes of Knee Protheses for Malignant Tumours of Bone

Clinical Results, Isokinetic Analysis and Radiologic Outcomes of Knee MUTARS Protheses Replacement for Malignant Tumours of Bone

rate of patients with successful locking will be estimated by the frequency observed Active locking of the operated knee

Functional results of patients with medullary reconstruction prosthesis,joint amplitudes in flexion-extension and in active, passive,

Functional results of patients with medullary reconstruction prosthesis

The MSTS Score may be used as a functional measure for patients with sarcoma involving the upper limb. The score includes 6 measures (pain, function, emotional acceptance, hand position, manual dexterity, lifting ability) each measure with a maximum of 5 points. The maximum overall score is 30 points. The score is designed to be used after the procedure and is therefore only collected post-operatively.

The Oxford Knee Score (OKS) is a Patient Reported Outcome questionnaire that was developed to specifically assess the patient's perspective of outcome following Total Knee Arthroplasty.

Each of the 12 answers are assigned the previously defined number of points. They range from 1 = least difficult to 5 = most difficult. The 12 ratings are then added together to give a total score used to assess the patient.

Functional results of patients with medullary reconstruction prosthesis

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a patient-reported outcome measurement instrument, developed to assess the patient's opinion about their knee and associated problems Functional results of patients with medullary reconstruction prosthesis

International Knee Society score : range 0 to 200, a higher score means a better outcome Functional results of patients with medullary reconstruction prosthesis

Radiological results of patients with medullary reconstruction prosthesis Radiological criterion : Lower limb axis,Blackburn and Peel index for patellar height, Radiological signs of loosening

Muscle recovery of the operated limb compared to the healthy limb

Muscle recovery of the operated limb compared to the healthy limb

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University Hospital, Lille

Symptoms and General Pathology

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Nervous System Diseases

Diseases and Abnormalities at or Before Birth

Skin and Connective Tissue Diseases

Hemorrhage

Prostatic Neoplasms

Osteoarthritis

Osteoarthritis, Hip

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Joint Diseases

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Congenital Abnormalities

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Coagulants

All Drugs and Chemicals

Thrombin

Hemostatics

according to the Thromboelastography (TEG) test, CK r-time prolongation, fresh frozen plasma transfusion (FFP) is performed

according to the Thromboelastography (TEG) test, CK r-time prolongation,prothrombin complex concentrate (PCC) administration

fresh frozen plasma

prothrombin complex concentrate administration

prothrombin complex concentrate

Tae-Yop Kim, MD PhD

The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for non-cardiac surgery.

Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery

Prothrombin Complex Concentrate and Fresh Frozen Plasma in Viscoelastic Test-based Goal-directed Bleeding Management in Non-Cardiac Surgery

Red Blood Cell transfusion amount during surgery

Platelet transfusion amount during surgery

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Functional Outcomes of Knee Protheses for Malignant Tumours of Bone	NCT04650594	Knee Disease Bone Cancer	MUTARS® modular...	18 Years -	University Hospital, Lille
Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery	NCT06144099	Prostate Cancer Spine, Open Hip Osteoarthri... Knee Disease	fresh frozen pl... prothrombin com...	20 Years - 80 Years	Konkuk University Medical Center

Spots Global Cancer Trial Database for knee disease

Every month we try and update this database with for knee disease cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.