Neoplasms

All Conditions

Respiratory Tract (Lung and Bronchial) Diseases

Ear, Nose, and Throat Diseases

Rare Diseases

Carcinoma

Laryngeal Neoplasms

Otorhinolaryngologic Neoplasms

Head and Neck Neoplasms

Laryngeal Diseases

Respiratory Tract Diseases

Respiratory Tract Neoplasms

Otorhinolaryngologic Diseases

Laryngeal Cancer

Patients undergoing endoscopic treatment with CO2 laser

Patients undergoing endoscopic treatment with KTP laser

surgical removal of carcinoma from the vocal cords with CO2 laser

CO2 laser

surgical removal of carcinoma from the vocal cords with KTP laser

KTP laser

Yonatan Lahav, Dr

Yaara Haimovich

comparison results of treatment of early stage glottic cancer between two methods of surgical treatment - CO2 laser and KTP laser

Randomized controlled double-blinded study. The study group includes patients diagnosed with early glottic cancer, either carcinoma in situ or T1a-b,N0M0 squamous cell carcinoma.

Patients will undergo examination and treatment and at least 3 years of follow-up.

40 cancer patients will be included. The participants will be randomly divided into two groups: the first will be treated by KTP laser and the second by CO2 laser.

The patients will be blinded to the method of treatment. To enable double-blinding, the investigator performing the surgery would be the only one knowing which research group the patient belongs to. The investigator in charge of collecting the data after the operation will be blinded to the treatment method.

Each participant will undergo pre-operative evaluation and follow-up after surgery in both arms.

Preoperative evaluation will include:

* Voice Handicap Index questionnaire
* GRBAS - subjective assessment of voice quality.
* Video-stroboscopy of vocal cords
* Voice Analysis .

Follow-up after surgery:

* Visit 6 weeks after surgery (± two weeks), and then every three months (± 6 weeks).
* repeated full evaluation (questionnaire, GRBAS, Stroboscopy, voice analysis) in 30 weeks of follow up and 3 years of follow up.

KTP vs CO2 Laser for the Treatment of Laryngeal Carcinoma

Comparison Between the Use of KTP Laser vs. CO2 Laser for Endoscopic Surgical Removal of Malignant Neoplasms of the Vocal Cords

total time (minutes) of surgical procedure

total number of surgical interventions needed to eliminate the disease

recovery in terms of overall function, breathing, swallowing and vocal communication

objective measurement- voice lab analysis, and subjective measurement- Voice Handicap Index questionnaire

evidence of malignant disease in the larynx, cervical lymph nodes or distant metastases

Kaplan Medical Center

Dr Yonatan Lahav

Hemangioma

Neoplasms, Vascular Tissue

Neoplasms by Histologic Type

Anti-Infective Agents

All Drugs and Chemicals

Dermatologic Agents

Chlorhexidine

Chlorhexidine gluconate

Each subject will receive a 532 nm KTP laser treatment for their spider angioma(s).

Dual Wavelength Laser Emitting 532 nm Laser Energy

Kelly Stankiewicz, MD FAAD

To evaluate the safety and effectiveness of the laser treatment for the treatment of spider angiomas.

The purpose of this study is to evaluate the safety and efficacy of the 532 nm KTP laser within the Cutera Excel V system for the treatment of spider angiomas.

Clinical Evaluation of the Treatment of Spider Angioma

A Clinical Evaluation of the Treatment of Spider Angioma Using a Dual Wavelength Laser Emitting 532 nm Laser Energy

Assessment of Baseline vs. 4 weeks post-final treatment for improvement of spider angiomas using the Physician's Global Assessment scale.

High scores indicate better outcomes:

0. None

1. Mild
2. Moderate
3. Significant
4. Very Significant
5. Complete Removal

Cutera Inc.

Each subject will receive a 532 nm KTP laser treatment for their spider angioma(s).

KTP laser: Dual Wavelength Laser Emitting 532 nm Laser Energy

Laser Treatment

Age, Continuous

Sex: Female, Male

United States

Region of Enrollment

Margot Doucette

Physician's Global Assessment Scale for Improvement of Spider Angioma

Overall Study

Symptoms and General Pathology

Mouth and Tooth Diseases

Recurrence

Nasopharyngeal Carcinoma

Neoplasms, Glandular and Epithelial

Nasopharyngeal Neoplasms

Pharyngeal Neoplasms

Nasopharyngeal Diseases

Pharyngeal Diseases

Stomatognathic Diseases

Ching-Ting Tan, MD, PhD

Investigate the treatment result of KTP laser nasopharyngectomy in recurrent NPC patients

Nasopharyngeal carcinomas (NPCs) are highly radiosensitive tumors, and the primary treatment of NPCs is radiotherapy.1 Because most patients who have NPC are at advanced stages when initially seen, local failures in terms of persistence or recurrence are not infrequent after primary radiotherapy.2,3 Local regional relapse without the presence of distant failure can still be salvaged and should be aggressively treated. Tumors relapsing in the nasopharynx can be salvaged using either re-irradiation or surgical techniques.1 Although re-irradiation to the recurrent tumor can extent the 5-year actuarial survival rate, it is associated with high morbidity. 4-6 Traditional nasopharyngectomy has been associated with local control rates on the order of 40%\~50%, but it has also been associated with complications such as palatal defects, trismus, facial scarring, osteomyelitis, etc.7-10 That is the reason why surgeons continue searching for new methods for performing nasopharyngectomies with lower morbidities.

Nasopharyngectomies are difficult to perform because of the inaccessibility of the nasopharynx. More difficulties are encountered in performing a nasopharyngectomy through the nose due to the restricted surgical field. With advances in techniques of endoscopy and application of the potassium-titanyl-phosphate (KTP) laser in surgery, pathologic lesions located either at the choanal margin or in the nasopharynx can easily be managed with instruments inserted via the nasal cavities. The surgical technique had been accepted by the authority journal. This time, we will review the therapeutic result of KTP-laser nasopharyngectomy in patients with recurrent NPC.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
KTP vs CO2 Laser for the Treatment of Laryngeal Carcinoma	NCT02672904	Laryngeal Neopl...	CO2 laser KTP laser	18 Years -	Kaplan Medical Center
Clinical Evaluation of the Treatment of Spider Angioma	NCT02755467	Spider Angioma	KTP laser	5 Years - 65 Years	Cutera Inc.
Clinical Evaluation of the Treatment of Spider Angioma	NCT02755467	Spider Angioma	KTP laser	5 Years - 65 Years	Cutera Inc.
Clinical Evaluation of the Treatment of Spider Angioma	NCT02755467	Spider Angioma	KTP laser	5 Years - 65 Years	Cutera Inc.
Treatment Result of KTP Laser Nasopharyngectomy in Recurrent NPC Patients	NCT00364962	Recurrent Nasopharyngeal ...		20 Years - 75 Years	National Taiwan University Hospital

Spots Global Cancer Trial Database for ktp laser

Every month we try and update this database with for ktp laser cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for ktp laser

Every month we try and update this database with for ktp laser cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for ktp laser cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.