Blood and Lymph Conditions

All Conditions

Neoplasms

Symptoms and General Pathology

Lymphedema

Neoplasm Metastasis

Neoplastic Processes

Lymphatic Diseases

Parallel control group, not undertaking any treatment and not part of the cross-over design

Two weeks rehabilitation programme focusing on physical therapy treatment, e.g. manual lymphatic drainage and compression bandaging

Physical therapy treatment

Two weeks rehabilitation programme focusing on physical activity

Lifestyle treatment

Participants with lymphedema secondary to cancer treatment will participate in a two week rehabilitation programme focusing on physical therapy treatment and a two week programme focusing on physical exercise. The purpose is to assess the effect of the rehabilitation programmes on lymphedema and measures of physical performance.

Traditionally, physical therapy treatment, e.g. manual lymphatic drainage and compression bandaging is used for treatment of cancer treatment induced lymphedema. Alternatively, lifestyle interventions are used as treatment, with focus on physical exercise. However, the effects of such interventions are scarcely documented. Thus, the purpose of this study is to assess the effect of physical therapy treatment and physical exercise on lymphedema and measures of physical performance.

The study will be performed in a randomized cross-over design, encompassing 26 participants with secondary lymphedema related to cancer treatment. Firstly, half of the participants in the intervention group will be randomized to a two week rehabilitation programme focusing on physical activity while the other half to a rehabilitation programme focusing on physical therapy treatment, and the other way around three months later. In addition. there will be a control group with cancer related lymphedema not participating in any rehabilitation programme. Pre and post of each of the two week rehabilitation periods the following measurements will be performed: The magnitude of lymphedema by volume measurements of the limbs (by DXA); measurements of maximal strength, range of movement, flexibility, balance, physical functionality and questionnaires about perceived health and level of physical activity.

26 participants will be enrolled in the cross over design consisting of two different rehabilitation programme. In addition there will be a parallel control group with 10 participants not participating in any of the rehabilitation programmes.

Effect of Lifestyle Intervention vs Physical Therapy Treatment in Patients With Secondary Lymphedema After Cancer

Ratio of the volume of affected limb vs volume of nonaffected limb measured by DXA

Perceived health assessed by questionnaire

Level of physical activity assessed by questionnaire

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Effect of Lifestyle Intervention vs Physical Therapy Treatment in Patients With Secondary Lymphedema After Cancer	NCT04196725	Lymphedema, Sec...	Physical therap... Lifestyle treat...	18 Years -	Inland Norway University of Applied Sciences
Effect of Lifestyle Intervention vs Physical Therapy Treatment in Patients With Secondary Lymphedema After Cancer	NCT04196725	Lymphedema, Sec...	Physical therap... Lifestyle treat...	18 Years -	Inland Norway University of Applied Sciences

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